ID H2NU33_PONAB Unreviewed; 416 AA.
AC H2NU33; A0A2J8WAM7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Keratin 36 {ECO:0000313|Ensembl:ENSPPYP00000009464.2};
GN Name=KRT36 {ECO:0000313|Ensembl:ENSPPYP00000009464.2};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000009464.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000009464.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPPYP00000009464.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2NU33; -.
DR STRING; 9601.ENSPPYP00000009464; -.
DR Ensembl; ENSPPYT00000009845.2; ENSPPYP00000009464.2; ENSPPYG00000008418.2.
DR eggNOG; ENOG502QQY9; Eukaryota.
DR GeneTree; ENSGT00940000161311; -.
DR HOGENOM; CLU_012560_8_0_1; -.
DR InParanoid; H2NU33; -.
DR OrthoDB; 4640531at2759; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000001595; Chromosome 17.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF204; KERATIN, TYPE I CUTICULAR HA6; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 43..354
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 47..81
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 146..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 305..339
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 416 AA; 47201 MW; 29427051E3FF3D9C CRC64;
MLRSGLSGLG SCLPGSYLSS GCHTSGFVGS GGWFCEGSFN GSEKETMQFL NDRLANYLEK
VRQLEQENAE LESRIREWYE SQIPYICPDY QSYFKTIEDF QQKILLTKSE NARLVLQIDN
AKLAADDFRT KYETELSLRQ LVEADINGLR RILDELTLCK ADLEAQVESL KEELTCLKKN
HEEEVSVLRC QLGDRLNVEV DAAPPVDLNK ILEDMRCQYE ALVENNRRDV EAWFNTQTEE
LNQQVVSSSE QLQCCQTEII ELRRTVNALE IELQAQHSMR NSLESTLAET EARYSSQMAQ
MQCLISNVEA QLSEIRCDLE RQNQEYQVLL DVKARLEGEI ATYRRLLEGE DCKLPPPPCA
TACKPAIRVP SVPPVPCPSV PCTPAPQVGT QIRTITEEIR DGKVISSREH VQSRPL
//
