ID   H2P048_PONAB            Unreviewed;       318 AA.
AC   H2P048;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 2.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Immunoglobulin subtype domain-containing protein {ECO:0000259|SMART:SM00409};
GN   Name=LOC100437371 {ECO:0000313|Ensembl:ENSPPYP00000011645.2};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000011645.2, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000011645.2, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000011645.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC       {ECO:0000256|ARBA:ARBA00008637}.
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DR   AlphaFoldDB; H2P048; -.
DR   Ensembl; ENSPPYT00000012089.2; ENSPPYP00000011645.2; ENSPPYG00000010391.3.
DR   eggNOG; ENOG502RU21; Eukaryota.
DR   GeneTree; ENSGT01100000263478; -.
DR   HOGENOM; CLU_021100_2_1_1; -.
DR   InParanoid; H2P048; -.
DR   OMA; CHRSPLK; -.
DR   TreeFam; TF352669; -.
DR   Proteomes; UP000001595; Chromosome 19.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05711; IgC2_D2_LILR_KIR_like; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   PANTHER; PTHR11738:SF168; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DL2-RELATED; 1.
DR   PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; Immunoglobulin; 2.
PE   3: Inferred from homology;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        225..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          15..104
FT                   /note="Immunoglobulin subtype"
FT                   /evidence="ECO:0000259|SMART:SM00409"
FT   DOMAIN          115..202
FT                   /note="Immunoglobulin subtype"
FT                   /evidence="ECO:0000259|SMART:SM00409"
SQ   SEQUENCE   318 AA;  35449 MW;  DA82B25A10A998C2 CRC64;
     QAAKRVHRKP SLLALPGPLV KSEETVILQC WSDVVFEHFL LHREGEFNDT LRLIGELHDG
     VSKVNFSIGP MMPTLAGTYR CYGSLSHSPY EWSAPSDPLD IMMTGLYEKP SLSAQPGPRV
     QAGENVTLSC SSRRSYDIYH LSREQGGREC RLPAVSKVNG TFQADFPLGP VTHGGTYRCF
     GSFRDSPYEW SNSSDPLLVS VTGNPSNSWP SPTKPSSKIG NPRHLHVLIG ISVVIIPFAI
     LLFFLLHRWC SNKKTFPSLQ DSDEQDPQEV TYAQLDHCVF TQRKITRPSQ RPKTPPTDTI
     VYTELPNAEP RSKVVSCP
//