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Database: UniProt
Entry: H2P0H7_PONAB
LinkDB: H2P0H7_PONAB
Original site: H2P0H7_PONAB 
ID   H2P0H7_PONAB            Unreviewed;       528 AA.
AC   H2P0H7;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   16-OCT-2019, entry version 54.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000011777};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000011777, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000011777, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000011777}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; ABGA01280720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01280721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9601.ENSPPYP00000011777; -.
DR   Ensembl; ENSPPYT00000012225; ENSPPYP00000011777; ENSPPYG00000010510.
DR   eggNOG; KOG2177; Eukaryota.
DR   eggNOG; ENOG4110P0K; LUCA.
DR   GeneTree; ENSGT00940000160527; -.
DR   InParanoid; H2P0H7; -.
DR   OMA; SEIDSAC; -.
DR   TreeFam; TF106455; -.
DR   Proteomes; UP000001595; Chromosome 19.
DR   GO; GO:0005719; C:nuclear euchromatin; IEA:Ensembl.
DR   GO; GO:0005720; C:nuclear heterochromatin; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0090575; C:RNA polymerase II transcription factor complex; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0043045; P:DNA methylation involved in embryo development; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0060669; P:embryonic placenta morphogenesis; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR   GO; GO:1901536; P:negative regulation of DNA demethylation; IEA:Ensembl.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:2000653; P:regulation of genetic imprinting; IEA:Ensembl.
DR   CDD; cd00021; BBOX; 1.
DR   CDD; cd16765; RING-HC_TIF1beta; 1.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR003649; Bbox_C.
DR   InterPro; IPR037373; KAP1.
DR   InterPro; IPR042713; TIF1beta_RING-HC.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR25462:SF274; PTHR25462:SF274; 2.
DR   Pfam; PF00643; zf-B_box; 2.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00502; BBC; 1.
DR   SMART; SM00336; BBOX; 2.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS50119; ZF_BBOX; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001595};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00139427};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW   Zinc {ECO:0000256|SAAS:SAAS00139522};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175,
KW   ECO:0000256|SAAS:SAAS00139444}.
FT   DOMAIN       65    122       RING-type. {ECO:0000259|PROSITE:PS50089}.
FT   DOMAIN      149    196       B box-type. {ECO:0000259|PROSITE:
FT                                PS50119}.
FT   DOMAIN      205    246       B box-type. {ECO:0000259|PROSITE:
FT                                PS50119}.
FT   REGION        1     51       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      412    471       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      507    528       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     30     48       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   528 AA;  56340 MW;  465DC8A3C6B8713B CRC64;
     MAASAAAASA AAASAVSGSP GPGEGSAGGE KRSTASSAAA SASASAAASS PAGGGAEALE
     LLEHCGVCRE RLRPEREPRL LPCLHSACSA CLGPAAPAAA ANSSGDGGAA GDGAVVDCPV
     CKQQCFSKDI VENYFMRDSG SKAATDAQDA NQCCTSCEDN APATSYCVEC SEPLCETCVE
     AHQRVKYTKD HTVRSTGPAK SRDGERTVYC NVHKHEPLVL FCESCDTLTC RDCQLNAHKD
     HQYQFLEDAV RNQRKLLASL VKRLGDKHAT LQKSTKEVRS SIRQVSDVQK RVQVDVKMAI
     LQIMKELNKR GRVLVNDAQK VTEGQQERLE RQHWTMTKIQ KHQEHILRFA SWALESDNNT
     ALLLSKKLIY FQLHRALKMI VDPVEPHGEM KFQWDLNAWT KSAEAFGKIV AERPGTNSTG
     PAPMAPPRAP GPLSKQGSGS SQPMEVQEGY GFGSGDDPYS SAEPHVSGVK DKADVQSIIG
     LQRFFETRMN EAFGDTKFSA VLVEPPPMSL PGAGLSSQEL SGGPGDGP
//
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