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Database: UniProt
Entry: H2PIV3_PONAB
LinkDB: H2PIV3_PONAB
Original site: H2PIV3_PONAB 
ID   H2PIV3_PONAB            Unreviewed;       341 AA.
AC   H2PIV3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   11-DEC-2019, entry version 46.
DE   SubName: Full=ETS variant 7 {ECO:0000313|Ensembl:ENSPPYP00000018506};
GN   Name=ETV7 {ECO:0000313|Ensembl:ENSPPYP00000018506};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000018506, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000018506, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000018506}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; ABGA01251840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01251841; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01251842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_002816853.1; XM_002816807.3.
DR   STRING; 9601.ENSPPYP00000018506; -.
DR   Ensembl; ENSPPYT00000019243; ENSPPYP00000018506; ENSPPYG00000016544.
DR   GeneID; 100451208; -.
DR   KEGG; pon:100451208; -.
DR   CTD; 51513; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000162211; -.
DR   InParanoid; H2PIV3; -.
DR   KO; K03211; -.
DR   OMA; RIQPSLW; -.
DR   OrthoDB; 827924at2759; -.
DR   TreeFam; TF318679; -.
DR   Proteomes; UP000001595; Chromosome 6.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT   DOMAIN          33..117
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          224..305
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          312..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  39025 MW;  4F00B17D7A973551 CRC64;
     MQEGELAISP ISPVAAMPPL GTDVQARCEA QINLLGEGGI CKLPGRLRIQ PTLWSREDVL
     HWLRWAEQEY SLPCTAEHGF EMNGRALCIL TKDDFRHRAP SSGDVLYELL QYIKTQRRAL
     VCGPFFGGAF RLKMPTQHSP VPPEEVTGPS QMDTRRGHLL QPPDPGLTSN FGHLDDPGLA
     RWTPGKEESL NLCHCAELGC RTQGVCSFPA MLQAPIDGRI ADCRLLWDYV YQLLLDTRYE
     PYIKWEDKDA KIFRVVDPDG LARLWGNHKN RMNMTYEKMS RALRHYYKLN IIKKEPGQKL
     LFRFLKTPGK MVQDKDSHLE PLDSQEQDRM EFKDKRPEIS P
//
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