ID H2PUE1_PONAB Unreviewed; 517 AA.
AC H2PUE1; A0A2J8SCI4; A0A5S6R7D5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=TRIM41 isoform 2 {ECO:0000313|EMBL:PNJ18481.1};
DE SubName: Full=Tripartite motif containing 41 {ECO:0000313|Ensembl:ENSPPYP00000022327.2};
GN Name=TRIM41 {ECO:0000313|Ensembl:ENSPPYP00000022327.2};
GN ORFNames=CR201_G0044112 {ECO:0000313|EMBL:PNJ18481.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000022327.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000022327.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ18481.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ18481.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000022327.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003584; PNJ18481.1; -; Genomic_DNA.
DR RefSeq; XP_009235195.1; XM_009236920.1.
DR STRING; 9601.ENSPPYP00000022327; -.
DR Ensembl; ENSPPYT00000023260.3; ENSPPYP00000022327.2; ENSPPYG00000019938.3.
DR GeneID; 100450991; -.
DR CTD; 90933; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000154294; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR OrthoDB; 3453019at2759; -.
DR TreeFam; TF342569; -.
DR Proteomes; UP000001595; Chromosome 5.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19760; Bbox2_TRIM4-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF659; E3 UBIQUITIN-PROTEIN LIGASE TRIM41; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 20..61
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 221..262
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 412..517
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 51..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 284..311
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 51..76
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..166
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 59231 MW; F8C48AF8FC6D5FD8 CRC64;
MAAVAMTPNP VQTLQEEAVC AICLDYFTDP VSIGCGHNFC RVCVTQLWGG EDEEDRDELD
REEEEEDGEE EEVEAVGAGA GWDTPMRDED YEGDMEEEVE EEEEGVFWTS GMSRSSWDNM
DYVWEEEDEE EDLDYYLGDM EEDLRGEDEE DEEEVLEEDE EEDLDPVTPL PPPPAPRRCF
TCPQCRKSFP RRSFRPNLQL ANMVQVIRQM HPTPGRGTRV TDQGICPKHQ EALKLFCEVD
EEAICVVCRE SRSHKQHSVV PLEEVVQEYK AKLQGHVEPL RKHLEAVQKM KAKEERRVTE
LKSQMKSELA AVASEFGRLT RFLAEEQAGL ERRLREMHEA QLGRAGAAAS RLAEQAAQLS
RLLAEAQERS QQGGLRLLQD IKETFNRCEE VQLQPPEVWS PDPCQPHSHD FLTDAIVRKM
SRMFCQAARV DLTLDPDTAH PALMLSPDRR GVRLAERRQE VADHPKRFSA DCCVLGAQGF
RSGRHYWEEP KEPSWPPARP SLTYYVCPTD RPEFSFT
//
