ID H2PX64_PONAB Unreviewed; 775 AA.
AC H2PX64; A0A2J8RLN5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=PDZ domain containing 4 {ECO:0000313|Ensembl:ENSPPYP00000023343.3};
DE SubName: Full=PDZD4 isoform 2 {ECO:0000313|EMBL:PNJ09395.1};
GN Name=PDZD4 {ECO:0000313|Ensembl:ENSPPYP00000023343.3};
GN ORFNames=CR201_G0049909 {ECO:0000313|EMBL:PNJ09395.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000023343.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000023343.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ09395.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ09395.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000023343.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003672; PNJ09395.1; -; Genomic_DNA.
DR Ensembl; ENSPPYT00000024320.3; ENSPPYP00000023343.3; ENSPPYG00000020857.3.
DR eggNOG; KOG0312; Eukaryota.
DR GeneTree; ENSGT00950000183062; -.
DR HOGENOM; CLU_011096_1_0_1; -.
DR OMA; EFMEGSP; -.
DR OrthoDB; 2879659at2759; -.
DR TreeFam; TF315909; -.
DR Proteomes; UP000001595; Chromosome X.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR15545; PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4; 1.
DR PANTHER; PTHR15545:SF4; PDZ DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 136..205
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 247..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 398..425
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 287..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 775 AA; 86876 MW; 28A7617A951AD2D6 CRC64;
MGCNMCVVQK PEEQYKVMLQ VNGKELSKLS QEQTLQALRS SKEPLVIQVL RRSPRLRGDS
SCHDLQLVDS GTQTDITFEH IMALGKLRPP TPPMVILEPY VLSELPPISH EYYDPAEFME
GGPQEADRLD ELEYEEVELY KSSHRDKLGL MVCYRTDDEE DLGIYVGEVN PNSIAAKDGR
IREGDRIIQI NGVDVQNREE AVAILSQEEN TNISLLVARP ESQLAKRWKD SDRDDFLDDF
GSENEGELRA RKLKSPPAQQ LGNEEEKGAP DAGPGLSNSQ ELDSGVGRTD ESTRNEESSE
HDLLGDEPPS STNTPGSLRK FGLQGDALQS RDFHFSMDSL LAEGAGLGGG DVPGLTDEEY
ERYRELLEIK CHLENGNQLG LLFPRASGGN SALDVNRNES LGHEMAMLEE ELRHLEFKCR
NILRAQKMQQ LRERCMKAWL LEEESLYDLA ASEPKKHELS DISELPEKSD KDSTSAYNTG
ESCRSTPLLV EPLPESPLRR AMAGNSNLNR TPPGLPVATP AKAAPPPGSP AKFRSLSRDP
EAGRRQHAEE RGRRNPKTGL TLERVGPEGS PYLSQRHRGQ GQEGEHYHSC VQLAPTRGLE
ELGHGPLSLA GGPRVGGVAA AATEAPRMEW KVKVRSDGTR YVAKRPVRDR LLKARALKIR
EERSGMTTDD DAVSEMKMGR YWSKEERKQH LIRAREQRKR REFMMQSRLE CLREQQNGDS
KPELNIIALS HRKTMKKRNK KILDNWITIQ EMLAHGARSA DGKRVYNPLL SVTTV
//
