ID H2Q0U4_PANTR Unreviewed; 909 AA.
AC H2Q0U4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Zinc finger and BTB domain containing 41 {ECO:0000313|Ensembl:ENSPTRP00000003016.7};
GN Name=ZBTB41 {ECO:0000313|Ensembl:ENSPTRP00000003016.7,
GN ECO:0000313|VGNC:VGNC:10876};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000003016.7, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000003016.7, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000003016.7}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04071383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2Q0U4; -.
DR Ensembl; ENSPTRT00000003279.7; ENSPTRP00000003016.7; ENSPTRG00000001808.7.
DR VGNC; VGNC:10876; ZBTB41.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00550000075080; -.
DR HOGENOM; CLU_014920_0_0_1; -.
DR InParanoid; H2Q0U4; -.
DR OMA; MVEKASF; -.
DR TreeFam; TF350933; -.
DR Proteomes; UP000002277; Chromosome 1.
DR Bgee; ENSPTRG00000001808; Expressed in pituitary gland and 21 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd18226; BTB_POZ_ZBTB41; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24404:SF49; RH47711P-RELATED; 1.
DR PANTHER; PTHR24404; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 12.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 88..152
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 207..230
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 361..388
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 389..416
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 422..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 463..490
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 491..519
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 518..546
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 547..574
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 575..602
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 603..630
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 631..659
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 696..723
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 724..752
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 252..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..299
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..320
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 105312 MW; CB2770079B541FA0 CRC64;
MKKRRKVTSN LEKIHLGYHK DSSEGNVAVE CDQVTYTHSA GRPTPEALHC YQELPPSPDQ
RKLLSSLQYN KNLLKYLNDD RQKQPSFCDL LIIVEGKEFS AHKVVVAVGS SYFHACLSKN
PSTDVVTLDH VTHSVFQHLL EFLYTSEFFV YKYEIPLVLE AAKFLDIIDA VKLLNNENVA
PFHSELTEKS SPEETLNELT GRLSNNHQCK FCSRHFCYKK SLENHLAKTH RSLLLGKKHG
LKMLERSFSA RRSKRNRKCP VKFDDTSDDE QESGDGSDNL NQENFDKEKS DRNDSEDPGS
EYNAEEDELE EEMSDEYSDI EEQSEKDHND AEEEPEAGDS VGNVHEGLTP VVIQNSNKKI
LQCPKCDKTF DRIGKYESHT RVHTGEKPFE CDICHQRYST KSNLTVHRKK HSNETEFHKK
EHKCPYCNKL HASKKTLAKH VKRFHPENAQ EFISIKKTKS ESWKCDICKK SFTRRPHLEE
HMILHSQDKP FKCTYCEEHF KSRFARLKHQ EKFHLGPFPC DICGRQFNDT GNLKRHIECT
HGGKRKWTCF ICGKSVRERT TLKEHLRIHS GEKPHLCSIC GQSFRHGSSY RLHLRVHHDD
KRYECDECGK TFIRHDHLTK HKKIHSGEKA HQCEECGKCF GRRDHLTVHY KSVHLGEKFW
QVFTLEVCYL KSLSYQVEYI LHLIIFLFIH IGEKPYKCQI CNQSFRIKKT LTKHLVIHSD
ARPFNCQHCN ATFKRKDKLK YHIDHVHEIK SPDDPLSTSE EKLVSLPVEY SSDDKIFQTE
TKQYMDQPKV YQSEAKTMLQ NVSAEVCVPV TLVPVQMPDT PSDLVRHTTT LPPSSHEILS
PQPQSTDYPR AADLAFLEKY TLTPQPANIV HPVRPEQMLD PREQSYLGTL LGLDSTTGVQ
NISTNEHHS
//
