ID H2Q297_PANTR Unreviewed; 1848 AA.
AC H2Q297;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=B-TFIID TATA-box binding protein associated factor 1 {ECO:0000313|Ensembl:ENSPTRP00000004803.5};
GN Name=BTAF1 {ECO:0000313|Ensembl:ENSPTRP00000004803.5,
GN ECO:0000313|VGNC:VGNC:11671};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000004803.5, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000004803.5, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000004803.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04051054; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPTRT00000005196.5; ENSPTRP00000004803.5; ENSPTRG00000002751.6.
DR VGNC; VGNC:11671; BTAF1.
DR eggNOG; KOG0392; Eukaryota.
DR GeneTree; ENSGT00940000157500; -.
DR HOGENOM; CLU_000315_1_1_1; -.
DR TreeFam; TF300546; -.
DR Proteomes; UP000002277; Chromosome 10.
DR Bgee; ENSPTRG00000002751; Expressed in lymph node and 21 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR CDD; cd17999; DEXHc_Mot1; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR044972; Mot1.
DR InterPro; IPR044078; Mot1_ATP-bd.
DR InterPro; IPR022707; Mot1_central_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR36498; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR PANTHER; PTHR36498:SF1; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR Pfam; PF12054; DUF3535; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1277..1452
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1635..1789
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 76..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1848 AA; 206758 MW; 1034C200F7E0F428 CRC64;
MGVQLDRLFI LLDTGTTPVT RKAAAQQLGE VVKLHPHELN NLLSKVLIYL RSANWDTRIA
AGQAVEAIVK NVPEWNPVPR TRQEPTSESS MEDSPTTERL NFDRFDICRL LQHGASLLGS
AGAEFEVQDE KSGEVDPKER IARQRKLLQK KLGLNMGEAI GMSTEELFND EDLDYTPTSA
SFVNKQPTLQ AAELIDSEFR AGMSNRQKNK AKRMAKLFAK QRSRDAVETN EKSNDSTDGE
PEEKRRKIAN VVINQSANDS KVLIDNIPDS SSLIEETNEW PLESFCEELC NDLFNPSWEV
RHGAGTGLRE ILKAHGKSGG KMGDSTLEEM IQQHQEWLED LVIRLLCVFA LDRFGDFVSD
EVVAPVRETC AQTLGVVLKH MNETGVHKTV DVLLKLLTQE QWEVRHGGLL GIKYALAVRQ
DVINTLLPKV LTRIIEGLQD LDDDVRAVAA ASLVPVVESL VYLQTQKVPF IINTLWDALL
ELDDLTASTN SIMTLLSSLL TYPQVQQCSI QQSLTVLVPR VWPFLHHTIS SVRRAALETL
FTLLSTQDQN SSSWLIPILP DMLRHIFQFC VLESSQEILD LIHKVWMELL SKASVQYVVA
AACPWMGAWL CLMMQPSHLP IDLNMLLEVK ARAKEKTGGK VRQGQSQNKE VLQEYIAGAD
TIMEDPATRD FVVMRARMMA AKLLGALCCC ICDPGVNVVT QEIKPAESLG QLLLFHLNSK
SALQRISVAL VICEWAALQK ECKAVTLAVQ PRLLDILSEH LYYDEIAVPF TRMQNECKQL
ISSLADVHIE VGNRVNNNVL TIDQASDLVT TVFNEATSSF DLNPQVLQQL DSKRQQVQMT
VTETNQEWQV LQLRVHTFAA CAVVSLQQLP EKLNPIIKPL METIKKEENT LVQNYAAQCI
AKLLQQCTTR TPCPNSKIIK NLCSSLCVDP YLTPCVTCPV PTQSGQENSK GSTSEKDGMH
HTVTKHRGII TLYRHQKAAF AITSRRGPTP KAVKAQIADL PAGSSGNILV ELDEAQKPYL
VQRRGAEFAL TTIVKHFGGE MAVKLPHLWD AMVGPLRNTI DINNFDGKSL LDKGDSPAQE
LVNSLQVFET AAASMDSELH PLLVQHLPHL YMCLQYPSTA VRHMAARCVG VMSKIATMET
MNIFLEKVLP WLGAIDDSVK QEGAIEALAC VMEQLDVGIV PYIVLLVVPV LGRMSDQTDS
VRFMATQCFA TLIRLMPLEA GIPDPPNMSA ELIQLKAKER HFLEQLLDGK KLENYKIPVP
INAELRKYQQ DGVNWLAFLN KYKLHGILCD DMGLGKTLQS ICILAGDHCH RAQEYARSKL
AECMPLPSLV VCPPTLTGHW VDEVGKFCSR EYLNPLHYTG PPTERIRLQH QVKRHNLIVA
SYDVVRNDID FFRNIKFNYC ILDEGHVIKN GKTKLSKAVK QLTANYRIIL SGTPIQNNVL
ELWSLFDFLM PGFLGTERQF AARYGKPILA SRDARSSSRE QEAGVLAMDA LHRQVLPFLL
RRMKEDVLQD LPPKIIQDYY CTLSPLQVQL YEDFAKSRAK CDVDETVSSA TLSEETEKPK
LKATGHVFQA LQYLRKLCNH PALVLTPQHP EFKTTAEKLA VQNSSLHDIQ HAPKLSALKQ
LLLDCGLGNG STSESGTESV VAQHRILIFC QLKSMLDIVE HDLLKPHLPS VTYLRLDGSI
PPGQRHSIVS RFNNDPSIDV LLLTTHVGGL GLNLTGADTV VFVEHDWNPM RDLQAMDRAH
RIGQKRVVNV YRLITRGTLE EKIMGLQKFK MNIANTVISQ ENSSLQSMGT DQLLDLFTLD
KDGKAEKADT STSGKASMKS ILENLSDLWD QEQYDSEYSL ENFMHSLK
//
