ID H2Q2R5_PANTR Unreviewed; 744 AA.
AC H2Q2R5; A0A2J8JPG3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 32 {ECO:0000313|EMBL:JAA10154.1};
DE SubName: Full=DEAH-box helicase 32 (putative) {ECO:0000313|Ensembl:ENSPTRP00000005367.3};
GN Name=DHX32 {ECO:0000313|EMBL:JAA10154.1,
GN ECO:0000313|Ensembl:ENSPTRP00000005367.3, ECO:0000313|VGNC:VGNC:7845};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000005367.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000005367.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA10154.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA10154.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA43691.1}, Skin {ECO:0000313|EMBL:JAA29515.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA17985.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000005367.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04039300; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01001184; JAA10154.1; -; mRNA.
DR EMBL; GABF01004160; JAA17985.1; -; mRNA.
DR EMBL; GABD01003585; JAA29515.1; -; mRNA.
DR EMBL; GABE01001048; JAA43691.1; -; mRNA.
DR RefSeq; XP_001138928.1; XM_001138928.4.
DR RefSeq; XP_016775082.1; XM_016919593.1.
DR RefSeq; XP_016775083.1; XM_016919594.1.
DR STRING; 9598.ENSPTRP00000005367; -.
DR PaxDb; 9598-ENSPTRP00000005367; -.
DR Ensembl; ENSPTRT00000005796.4; ENSPTRP00000005367.3; ENSPTRG00000003044.6.
DR GeneID; 736293; -.
DR KEGG; ptr:736293; -.
DR CTD; 55760; -.
DR VGNC; VGNC:7845; DHX32.
DR eggNOG; KOG0925; Eukaryota.
DR GeneTree; ENSGT00940000157227; -.
DR HOGENOM; CLU_001832_5_11_1; -.
DR OMA; CTQVHKP; -.
DR OrthoDB; 5488182at2759; -.
DR TreeFam; TF105735; -.
DR Proteomes; UP000002277; Chromosome 10.
DR Bgee; ENSPTRG00000003044; Expressed in heart and 21 other cell types or tissues.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd17977; DEXHc_DHX32; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF88; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX32-RELATED; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00847; HA2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 457..548
FT /note="Helicase-associated"
FT /evidence="ECO:0000259|SMART:SM00847"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 84520 MW; BCE24550E6F39DEB CRC64;
MEEEGLECPN SSSEKRYFPE SLDSSDGDEE EVLACEDLEL NPFDGLPYSS RYYKLLKERE
DLPIWKEKYS FMENLLQNQI VIVSGDAKCG KSSQVPQWCA EYCLSIHYQH GGVICTQVHK
QTVVQLALRV ADEMDVNIGH EVGYVIPFEN CCTNETILRY CTDDMLQREM MSNPFLGSYG
VIILDDIHER SIATDVLLGL LKDILLARPE LKLIINSSPH LISKLNSYYG NVPVIEVKNK
HPVEVVYLSE AQKDSFESIL RLIFEIHHSG EKGDIVVFLA CEQDIEKVCE TVYQGSNLNP
DLGELVVVPL YPKEKCSLFK PLDETEKRCQ VYQRRVVLTT SSGEFLIWSN SVRFVIDVGV
ERRKVYNPRI RANSLVMQPI SQSQAEIRKQ ILGSSSSGKF FCLYTEEFAS KDMTPLKPAE
MQEANLTSMV LFMKRIDIAG LGHCDFMNRP APESLMQALE DLDYLAALDN DGNLSEFGII
MSEFPLDPQL SKSILASCEF DCVDEVLTIA AMVTAPNCFS HVPHGAEEAA LTCWKTFLHP
EGDHFTLISI YKAYQDTTLN SSSEYCVEKW CRDYFLNCSA LRMADVIRAE LLEIIKRIEL
PYAEPAFGSK ENTLNIKKAL LSGYFMQIAR DVDGSGNYLM LTHKQVAQLH PLSGYSITKK
MPEWVLFHKF SISENNYIRI TSEISPELFM QLVPQYYFSN LPPSESKDIL QQVVDHLSPV
STMNKEQQMC ETCPETAEQR CTLQ
//
