ID H2Q9Q5_PANTR Unreviewed; 691 AA.
AC H2Q9Q5; A0A2J8NQP7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Leucine rich repeat containing 49 {ECO:0000313|Ensembl:ENSPTRP00000012374.4};
GN Name=LRRC49 {ECO:0000313|Ensembl:ENSPTRP00000012374.4,
GN ECO:0000313|VGNC:VGNC:13406};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000012374.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000012374.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000012374.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04064646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04064647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009427308.1; XM_009429033.2.
DR AlphaFoldDB; H2Q9Q5; -.
DR STRING; 9598.ENSPTRP00000012374; -.
DR PaxDb; 9598-ENSPTRP00000012374; -.
DR Ensembl; ENSPTRT00000013352.4; ENSPTRP00000012374.4; ENSPTRG00000007236.4.
DR GeneID; 467718; -.
DR CTD; 54839; -.
DR VGNC; VGNC:13406; LRRC49.
DR GeneTree; ENSGT00940000157011; -.
DR InParanoid; H2Q9Q5; -.
DR OrthoDB; 5482204at2759; -.
DR TreeFam; TF324815; -.
DR Proteomes; UP000002277; Chromosome 15.
DR Bgee; ENSPTRG00000007236; Expressed in pituitary gland and 17 other cell types or tissues.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45973:SF9; CENTROSOMAL PROTEIN 97KDA, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 7.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 365..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 311..344
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 691 AA; 79553 MW; AA51A2C9616A003B CRC64;
MIPGKYRSVS GRAANNVNCG LHLVIQTSSL PEKNKVRFKK VEFKLNKDTS SFPGRLLQHD
LERNYSSRQG DHINLVSSSL SSFPILQRSS EEKILYSDRL SLERQKLTVC PIINGEDHLR
LLNFQHNFIT RIQNISNLQK LISLDLYDNQ IEEISGLSTL RCLRVLLLGK NRIKKISNLE
NLKSLDVLDL HGNQITKIEN INHLCELRVL NLARNFLSHV DNLNGLDSLT ELNLRHNQIT
FVRDVDNLPC LQHLFLSFNN ISSFDSVSCL ADSSSLSDIT FDGNPIAQES WYKHTVLQNM
MQLRQLDMKR ITEEERRMAS VLAKKEEEKK RESHKQSLLK EKRRLTINNV ARQWDLQQQR
VANIATNEDR KDSDSPQDPC QIDGSTLSAF PEETGPLDSG LNNALQGLSV IDTYLVEVDG
DTLSLYGSGA LESLDRNWSV QTAGMITTVS FTFIEFDEIV QVLPKLKIKF PNSLHLKFKE
TNLVMLQQFN ALAQLRRIDQ LTIDPQGNPV VNFTLWKYYV LFRLSHFSMQ KINGTEVTQN
DMIMAERLFG ILAHVASSEL PQYRLISILG DARKKQFQYL LESKGKKPGI INEENNDSKR
LVGENTNRAT LNYTTRDFYN EKLEEIKEKK KFCKTYIEDL VKEATEINMK NEALQKLWPQ
MFIELVRDAV IEIRNKNSYM KLCLQQITDQ K
//
