ID H2QBP9_PANTR Unreviewed; 197 AA.
AC H2QBP9; A0A2J8IWE6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Interleukin 17C {ECO:0000313|Ensembl:ENSPTRP00000014420.3};
GN Name=IL17C {ECO:0000313|Ensembl:ENSPTRP00000014420.3,
GN ECO:0000313|VGNC:VGNC:5807};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000014420.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000014420.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000014420.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
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DR EMBL; AACZ04071745; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2QBP9; -.
DR STRING; 9598.ENSPTRP00000014420; -.
DR PaxDb; 9598-ENSPTRP00000014420; -.
DR Ensembl; ENSPTRT00000015582.4; ENSPTRP00000014420.3; ENSPTRG00000008457.4.
DR VGNC; VGNC:5807; IL17C.
DR eggNOG; ENOG502S2UJ; Eukaryota.
DR GeneTree; ENSGT00940000161887; -.
DR HOGENOM; CLU_121730_0_0_1; -.
DR InParanoid; H2QBP9; -.
DR OMA; FAFHAEF; -.
DR TreeFam; TF314701; -.
DR Proteomes; UP000002277; Chromosome 16.
DR Bgee; ENSPTRG00000008457; Expressed in bone marrow and 2 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..197
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015092596"
SQ SEQUENCE 197 AA; 21774 MW; 8915B4A718C6EC8B CRC64;
MTLLPGLLFL TWLHTCLAHH DPSLRGHPHS HGTPHCYSAE ELPLGHAPPH LLARGAKWGQ
ALPVALVSSL EAASHRGRHE RPSATTQCPV LRPEEVLEAD THQRSISPWR YRVDTDEDRY
PQKLAFAECL CRGCIDARTG RETAALNSVR LLQSLLVLRR RPCSRDGSGL PTPGAFAFHT
EFIHVPVGCT CVLPRSV
//
