ID H2QBZ7_PANTR Unreviewed; 444 AA.
AC H2QBZ7; A0A2J8KQJ5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Zinc finger protein 232 {ECO:0000313|Ensembl:ENSPTRP00000014716.3};
GN Name=ZNF232 {ECO:0000313|Ensembl:ENSPTRP00000014716.3,
GN ECO:0000313|VGNC:VGNC:9805};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000014716.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000014716.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000014716.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
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DR EMBL; AC196241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2QBZ7; -.
DR STRING; 9598.ENSPTRP00000014716; -.
DR PaxDb; 9598-ENSPTRP00000014716; -.
DR Ensembl; ENSPTRT00000015902.4; ENSPTRP00000014716.3; ENSPTRG00000008623.4.
DR VGNC; VGNC:9805; ZNF232.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000163214; -.
DR HOGENOM; CLU_002678_49_3_1; -.
DR InParanoid; H2QBZ7; -.
DR OMA; QVLCCEW; -.
DR TreeFam; TF338304; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000008623; Expressed in testis and 19 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23226; ZINC FINGER AND SCAN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23226:SF54; ZINC FINGER PROTEIN 232; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 5.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 79..161
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 303..330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 331..358
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 359..386
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 387..414
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 415..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 161..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 50641 MW; C335D2B8114E3523 CRC64;
MEPPGPVTGP LQDSSWYEPS AELVQTRMAV SLTAAETLAL QGTQGQEKMM MMGPKEEEQS
CEYETRLPGN HSTSQEIFRQ RFRHLRYQET PGPREALSQL RVLCCEWLRP EKHTKEQILE
FLVLEQFLTI LPEELQSWVR GHHPKSGEEA VTVLEDLEKG LEPEPQVPGP AHGPAQEEPW
EKKESLGAAQ EALSIQLQPK ETQPFPKSEQ VYLHFLSVVT EDGPEPKDKG SLPQPPITEV
ESQVFSEKLA TDTSTFEATS EGTLELQQRN PKAERLRWSP AQEKSFRQMV VIHKEIPTGK
KDHECSECGK TFIYNSHLVV HQRVHSGEKP YKCSDCGKTF KQSSNLGQHQ RIHTGEKPFE
CNECGKAFRW GAHLVQHQRI HSGEKPYECN ECGKAFSQSS YLSQHRRIHS GEKPFICKEC
GKAYGWCSEL IRHRRVHARK EPSH
//
