ID H2QC14_PANTR Unreviewed; 301 AA.
AC H2QC14; A0A2J8KQ34;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=XIAP associated factor 1 {ECO:0000313|EMBL:JAA05506.1, ECO:0000313|Ensembl:ENSPTRP00000014760.3};
GN Name=XAF1 {ECO:0000313|EMBL:JAA05506.1,
GN ECO:0000313|Ensembl:ENSPTRP00000014760.3, ECO:0000313|VGNC:VGNC:9789};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000014760.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000014760.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA05506.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA05506.1}, Skin
RC {ECO:0000313|EMBL:JAA25894.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA16858.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000014760.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04040199; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01005832; JAA05506.1; -; mRNA.
DR EMBL; GABC01005831; JAA05507.1; -; mRNA.
DR EMBL; GABC01005830; JAA05508.1; -; mRNA.
DR EMBL; GABC01005829; JAA05509.1; -; mRNA.
DR EMBL; GABF01005287; JAA16858.1; -; mRNA.
DR EMBL; GABF01005286; JAA16859.1; -; mRNA.
DR EMBL; GABF01005285; JAA16860.1; -; mRNA.
DR EMBL; GABD01007206; JAA25894.1; -; mRNA.
DR EMBL; GABD01007205; JAA25895.1; -; mRNA.
DR EMBL; GABD01007204; JAA25896.1; -; mRNA.
DR EMBL; GABD01007203; JAA25897.1; -; mRNA.
DR EMBL; GABD01007202; JAA25898.1; -; mRNA.
DR EMBL; GABD01007201; JAA25899.1; -; mRNA.
DR RefSeq; XP_016786870.1; XM_016931381.1.
DR STRING; 9598.ENSPTRP00000014760; -.
DR PaxDb; 9598-ENSPTRP00000014760; -.
DR Ensembl; ENSPTRT00000015953.4; ENSPTRP00000014760.3; ENSPTRG00000008649.6.
DR GeneID; 455244; -.
DR CTD; 54739; -.
DR VGNC; VGNC:9789; XAF1.
DR eggNOG; ENOG502QQRU; Eukaryota.
DR GeneTree; ENSGT00530000063869; -.
DR HOGENOM; CLU_066148_0_0_1; -.
DR OMA; WHEAKCQ; -.
DR OrthoDB; 164168at2759; -.
DR TreeFam; TF331416; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000008649; Expressed in spleen and 20 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0140313; F:molecular sequestering activity; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0032480; P:negative regulation of type I interferon production; IEA:Ensembl.
DR GO; GO:0035456; P:response to interferon-beta; IEA:Ensembl.
DR Gene3D; 6.10.250.1730; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR049439; TRAFD1-XIAF1_Znf.
DR InterPro; IPR041386; XAF1_C.
DR InterPro; IPR031220; XAF1_C_sf.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR16295; TRAF-TYPE ZINC FINGER PROTEIN-RELATED; 1.
DR PANTHER; PTHR16295:SF17; XIAP-ASSOCIATED FACTOR 1; 1.
DR Pfam; PF21366; TRAFD1-XIAF1_ZnF; 1.
DR Pfam; PF18608; XAF1_C; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 23..99
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 23..99
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 188..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 301 AA; 34653 MW; 0A42B29CF96BE6E8 CRC64;
MEGDFSVCRN CKRHVVSANF TLHEAYCLRF LVLCPECEEP VPKETTEEHC KVEHQQVGCT
MCQQSMQKSS LEFHKANECQ ERPVECKFCK LDMQLSKLEL HESYCGSRTE LCQGCGQFIM
HRMLAQHRDV CRSEQAQLGK GERISAPERE IYCHYCNQMI PENKYFHHMG KCCPDSEFKK
HFPVGKPKIL PSSLPSQVAE NQTSTMEKDV RPKTRSINRF PLHSESSSKK APRSKNKTLD
PLLMSEPKPR TSSPRGDKAA YDILRRCSQC GILLPLPILN QHQEKCWWLA SSKGKQVRNF
S
//
