ID H2QJM2_PANTR Unreviewed; 239 AA.
AC H2QJM2; A0A2J8NEW1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=EF-hand domain family member D1 {ECO:0000313|Ensembl:ENSPTRP00000064927.1};
DE SubName: Full=EF-hand domain family, member D1 {ECO:0000313|EMBL:JAA26237.1};
GN Name=EFHD1 {ECO:0000313|EMBL:JAA26237.1,
GN ECO:0000313|Ensembl:ENSPTRP00000064927.1, ECO:0000313|VGNC:VGNC:369};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000064927.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000064927.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA26237.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skin {ECO:0000313|EMBL:JAA26237.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000064927.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04056642; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04056643; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABD01006863; JAA26237.1; -; mRNA.
DR STRING; 9598.ENSPTRP00000064927; -.
DR PaxDb; 9598-ENSPTRP00000022301; -.
DR Ensembl; ENSPTRT00000094273.1; ENSPTRP00000064927.1; ENSPTRG00000045721.1.
DR VGNC; VGNC:369; EFHD1.
DR eggNOG; KOG0041; Eukaryota.
DR GeneTree; ENSGT00390000012058; -.
DR HOGENOM; CLU_094429_0_0_1; -.
DR OMA; QTFNRFD; -.
DR OrthoDB; 2332111at2759; -.
DR TreeFam; TF320736; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000045721; Expressed in adult mammalian kidney and 18 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0061891; F:calcium ion sensor activity; IBA:GO_Central.
DR GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR GO; GO:1900069; P:regulation of cellular hyperosmotic salinity response; IEA:Ensembl.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR040365; EFHD1/2.
DR PANTHER; PTHR13025; EF-HAND DOMAIN-CONTAINING PROTEIN D; 1.
DR PANTHER; PTHR13025:SF5; EF-HAND DOMAIN-CONTAINING PROTEIN D1; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 90..125
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 126..161
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 202..231
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..45
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 239 AA; 26928 MW; 1712F79E2A3CC007 CRC64;
MASEELACKL ERRLRREEAE ESGPQLAPLG APAPEPKPEP EPPARAPTAS ADAELSAQLS
RRLDINEGAA RPRRCRVFNP YTEFPEFSRR LIKDLESMFK LYDAGRDGFI DLMELKLMME
KLGAPQTHLG LKSMIKEVDE DFDGKLSFRE FLLIFHKAAA GELQEDSGLM ALAKLSEIDV
ALEGVKGAKN FFEAKVQALS SASKFEAELK AEQDERKREE EERRLRQAAF QKLKANFNT
//
