ID   H2QKC7_PANTR            Unreviewed;       607 AA.
AC   H2QKC7; K7BF81;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   27-MAR-2024, entry version 64.
DE   RecName: Full=Actin-related protein 5 {ECO:0000256|ARBA:ARBA00021612};
GN   Name=ACTR5 {ECO:0000313|EMBL:JAA05322.1,
GN   ECO:0000313|Ensembl:ENSPTRP00000023164.4, ECO:0000313|VGNC:VGNC:9820};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000023164.4, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000023164.4, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|EMBL:JAA05322.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA05322.1};
RA   Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT   "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT   mRNA sequences.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPTRP00000023164.4}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP5 subfamily.
CC       {ECO:0000256|ARBA:ARBA00006021}.
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DR   EMBL; AACZ04052790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GABC01006016; JAA05322.1; -; mRNA.
DR   RefSeq; XP_001145158.2; XM_001145158.5.
DR   PaxDb; 9598-ENSPTRP00000023164; -.
DR   Ensembl; ENSPTRT00000025100.4; ENSPTRP00000023164.4; ENSPTRG00000013493.6.
DR   GeneID; 458246; -.
DR   KEGG; ptr:458246; -.
DR   CTD; 79913; -.
DR   VGNC; VGNC:9820; ACTR5.
DR   eggNOG; KOG0681; Eukaryota.
DR   GeneTree; ENSGT00720000108866; -.
DR   HOGENOM; CLU_008246_2_0_1; -.
DR   OMA; CYVSQDY; -.
DR   OrthoDB; 196861at2759; -.
DR   TreeFam; TF324227; -.
DR   Proteomes; UP000002277; Chromosome 20.
DR   Bgee; ENSPTRG00000013493; Expressed in testis and 18 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0031011; C:Ino80 complex; IBA:GO_Central.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0033044; P:regulation of chromosome organization; IEA:Ensembl.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0060382; P:regulation of DNA strand elongation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR   GO; GO:0070914; P:UV-damage excision repair; IEA:Ensembl.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; ACTIN; 1.
DR   PANTHER; PTHR11937:SF16; ACTIN-RELATED PROTEIN 5; 1.
DR   Pfam; PF00022; Actin; 2.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00432; ACTINS_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT   REGION          584..607
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          291..325
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   607 AA;  68285 MW;  84876DE161CAB956 CRC64;
     MAANVFPFRD ARAAPDPVLE TGPVAHGPLP VPLVLDNGSF QVRAGWACPG QDPGPEPRLQ
     FRAVCARGRG GARGASGPQV GNALGSLEPL RWMLRSPFDR NVPVNLELQE LLLDYSFQHL
     GVSSQGCVDH PIVLTEAVCN PLYSRQMMSE LLFECYGIPK VAYGIDSLFS FYHNKPKNSM
     CSGLIISSGY QCTHVLPILE GRLDAKNCKR INLGGSQAAG YLQRLLQLKY PGHLAAITLS
     RMEEILHEHS YIAEDYVEEL HKWRCPDYYE NNVHKMQLPF SSKLLGSTLT SEEKQERRQQ
     QLRRLQELNA RRREEKLQLD QERLDRLLYV QELLEDGQMD QFHKALIELN MDSPEELQSY
     IQKLSLAVEQ AKQKILQAEV NLEVDVVDSK PETPDLEQLE PSLEDVESMN DFDPLFSEET
     PGVEKPVTTV QPVFNLAAYH QLFVGTERIR APEIIFQPSL IGEEQAGIAE TLQYILDRYP
     KDVQEMLVQN VFLTGGNTMY PGMKARMEKE LLEMRPFQSS FQVQLASNPV LDAWYGARDW
     ALNHLDDNEV WITRKEYEEK GGEYLKEHCA SNIYVPIRLP KQASRSSDAQ ASSKGSAAGG
     GGAGEQA
//