ID   H2QN83_PANTR            Unreviewed;       489 AA.
AC   H2QN83;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=HSPB (Heat shock 27kDa) associated protein 1 {ECO:0000313|EMBL:JAA01875.1};
DE   SubName: Full=HSPB1 associated protein 1 {ECO:0000313|Ensembl:ENSPTRP00000026374.2};
GN   Name=HSPBAP1 {ECO:0000313|EMBL:JAA01875.1,
GN   ECO:0000313|Ensembl:ENSPTRP00000026374.2, ECO:0000313|VGNC:VGNC:7069};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000026374.2, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000026374.2, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|EMBL:JAA01875.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA01875.1}, Skeletal muscle
RC   {ECO:0000313|EMBL:JAA35368.1}, and Skin {ECO:0000313|EMBL:JAA32033.1};
RA   Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT   "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT   mRNA sequences.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPTRP00000026374.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: May play a role in cellular stress response.
CC       {ECO:0000256|ARBA:ARBA00037342}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; AACZ04048118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04048119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04048120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; GABC01009463; JAA01875.1; -; mRNA.
DR   EMBL; GABD01001067; JAA32033.1; -; mRNA.
DR   EMBL; GABE01009371; JAA35368.1; -; mRNA.
DR   RefSeq; XP_009444248.1; XM_009445973.2.
DR   PaxDb; 9598-ENSPTRP00000026374; -.
DR   Ensembl; ENSPTRT00000028574.3; ENSPTRP00000026374.2; ENSPTRG00000015298.6.
DR   GeneID; 460635; -.
DR   CTD; 79663; -.
DR   VGNC; VGNC:7069; HSPBAP1.
DR   eggNOG; KOG2132; Eukaryota.
DR   GeneTree; ENSGT00940000159893; -.
DR   HOGENOM; CLU_016785_5_1_1; -.
DR   OrthoDB; 5401772at2759; -.
DR   TreeFam; TF315056; -.
DR   Proteomes; UP000002277; Chromosome 3.
DR   Bgee; ENSPTRG00000015298; Expressed in skeletal muscle tissue and 20 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.120.650; Cupin; 1.
DR   InterPro; IPR041667; Cupin_8.
DR   InterPro; IPR013296; HSPB1-associated_protein_1.
DR   InterPro; IPR003347; JmjC_dom.
DR   PANTHER; PTHR12461:SF43; HSPB1-ASSOCIATED PROTEIN 1; 1.
DR   PANTHER; PTHR12461; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED; 1.
DR   Pfam; PF13621; Cupin_8; 1.
DR   PRINTS; PR01886; PASS1.
DR   SMART; SM00558; JmjC; 1.
DR   SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR   PROSITE; PS51184; JMJC; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Stress response {ECO:0000313|EMBL:JAA01875.1}.
FT   DOMAIN          124..288
FT                   /note="JmjC"
FT                   /evidence="ECO:0000259|PROSITE:PS51184"
FT   REGION          369..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  55299 MW;  8C998F9406146B5D CRC64;
     MAAGSEATTP VIVAAGAGGE EGEHVKPFKP EKAKEIIMSL QQPAIFCNMV FDWPARHWNA
     KYLSQVLHGK QIRFRMGMKS MSTVPQFETT CNYVEATLEE FLTWNCDQSS ISGPFRDYDH
     SKFWAYADYK YFVSLFEDKT DIFQDVKWSD FGFPGRNGQE STLWIGSLGA HTPCHLDSYG
     CNLVFQVQGR KRWHLFPPED TPFLYPTRIP YEESSVFSKI NVVNPDLKRF PQFRKAQRHT
     VTLSPGQVLF VPRHWWHYVE SIDPVTVSIN SWIELEEDHL ARVEEAITRM LVCALKTAEN
     PQNTRAWLNP TEVEETSHAV NCCYLNAAVS AFFDRCRTSE VVEIQALRTD GEHMKKEELN
     VCNHMEVGQT GSQNLTTGTD KPEAASPFGP DLVPVAQRSE EPPSERGGIF GSDGKDFVDK
     DGEHFGKLHC AKRQQIMSNS ENAIEEQIAS NTTKAPSQTF ISTDDLLDCL VNPQVTRMVA
     QLLIQGRSL
//