ID H2QT30_PANTR Unreviewed; 538 AA.
AC H2QT30;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=GTP binding protein 2 {ECO:0000313|Ensembl:ENSPTRP00000031112.4};
GN Name=GTPBP2 {ECO:0000313|Ensembl:ENSPTRP00000031112.4,
GN ECO:0000313|VGNC:VGNC:2853};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000031112.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000031112.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000031112.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04022883; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2QT30; -.
DR Ensembl; ENSPTRT00000033667.4; ENSPTRP00000031112.4; ENSPTRG00000018206.6.
DR VGNC; VGNC:2853; GTPBP2.
DR eggNOG; KOG1143; Eukaryota.
DR GeneTree; ENSGT00940000155636; -.
DR HOGENOM; CLU_012821_1_1_1; -.
DR TreeFam; TF350446; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018206; Expressed in bone marrow and 21 other cell types or tissues.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04165; GTPBP1_like; 1.
DR CDD; cd03694; GTPBP_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR035531; GTPBP1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF3; GTP-BINDING PROTEIN 2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 118..346
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 538 AA; 59506 MW; 6FEA385B37E0EC6A CRC64;
MWTKAMDSTK SEPLKGSPEL KLVNPSQYRF EHLVTQMKWR LQEGRGEAVY QIGVEDNGLL
VGLAEEEMRA SLKTLHRMAE KVGADITVLR EREVDYDSDM PRKITEVLVR KVPDNQQFLD
LRVAVLGNVD SGKSTLLGVL TQGELDNGRG RARLNLFRHL HEIQSGRTSS ISFEILGFNS
KGEVVNYSDS RTAEEICESS SKMITFIDLA GHHKYLHTTI FGLTSYCPDC ALLLVSANTG
IAGTTREHLG LALALKVPFF IVVSKIDLCA KTTVERTVRQ LERVLKQPGC HKVPMLVTSE
DDAVTAAQQF AQSPNVTPIF TLSSVSGESL DLLKVFLNIL PPLTNSKEQE ELMQQLTEFQ
VDEIYTVPEV GTVVGGTLSS GICREGDQLV VGPTDDGCFL ELRVCSIQRN RSACRVLRAG
QAATLALGDF DRALLRKGMV MVSPEMNPTI CSVFEAEIVL LFHATTFRRG FQVTVHVGNV
RQTAVVEKIH AKDKLRTGEK AVVRFRFLKH PEGVLSATCS LPTFWRGAKF GVARKGQS
//
