ID H2QTH8_PANTR Unreviewed; 399 AA.
AC H2QTH8; A0A2J8PUM4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Decaprenyl diphosphate synthase subunit 2 {ECO:0000313|Ensembl:ENSPTRP00000031540.3};
DE SubName: Full=Prenyl (Decaprenyl) diphosphate synthase, subunit 2 {ECO:0000313|EMBL:JAA01392.1};
GN Name=PDSS2 {ECO:0000313|EMBL:JAA01392.1,
GN ECO:0000313|Ensembl:ENSPTRP00000031540.3,
GN ECO:0000313|VGNC:VGNC:14792};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000031540.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000031540.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA01392.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA01392.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA41094.1}, Skin {ECO:0000313|EMBL:JAA27445.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA21573.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000031540.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; AACZ04069872; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04069873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04069874; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC191739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01009946; JAA01392.1; -; mRNA.
DR EMBL; GABF01000572; JAA21573.1; -; mRNA.
DR EMBL; GABF01000571; JAA21574.1; -; mRNA.
DR EMBL; GABF01000570; JAA21575.1; -; mRNA.
DR EMBL; GABD01005655; JAA27445.1; -; mRNA.
DR EMBL; GABD01005654; JAA27446.1; -; mRNA.
DR EMBL; GABD01005653; JAA27447.1; -; mRNA.
DR EMBL; GABE01003645; JAA41094.1; -; mRNA.
DR RefSeq; XP_001146753.1; XM_001146753.5.
DR STRING; 9598.ENSPTRP00000031540; -.
DR PaxDb; 9598-ENSPTRP00000031540; -.
DR Ensembl; ENSPTRT00000034125.4; ENSPTRP00000031540.3; ENSPTRG00000018466.6.
DR GeneID; 462912; -.
DR KEGG; ptr:462912; -.
DR CTD; 57107; -.
DR VGNC; VGNC:14792; PDSS2.
DR eggNOG; KOG0776; Eukaryota.
DR GeneTree; ENSGT00940000153498; -.
DR HOGENOM; CLU_014015_3_1_1; -.
DR OMA; HEQVRWT; -.
DR OrthoDB; 2899987at2759; -.
DR TreeFam; TF354277; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018466; Expressed in fibroblast and 21 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:1990234; C:transferase complex; IBA:GO_Central.
DR GO; GO:0097269; F:all-trans-decaprenyl-diphosphate synthase activity; IEA:Ensembl.
DR GO; GO:0052923; F:all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity; IEA:Ensembl.
DR GO; GO:0004659; F:prenyltransferase activity; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR GO; GO:0000010; F:trans-hexaprenyltranstransferase activity; IEA:Ensembl.
DR GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IBA:GO_Central.
DR GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR PANTHER; PTHR12001:SF55; ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 2: Evidence at transcript level;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 399 AA; 44055 MW; 6AE1A76A97BCDFC0 CRC64;
MNLRQLLLHL PRYLGASGSP RRLWWSPSLD TISSVGSWRG QSSKSPAHWN QVVSEAEKIV
GYPTSFMSLR CLLSDELSNI AMQVRKLVGT QHPLLTTARG LVHDSWNSLQ LRGLVVLLIS
KAAGPSSVNT SCQNYDMVSG IYSCQRSLAE ITELIHTALL VHRGIVNLNE LQSSDGPLKD
MQFGNKIAIL SGDFLLANAC NGLALLQNTK VVELLASALM DLVQGVYHEN STSKESYITD
DIGISTWKEQ TFLSHGALLA KSCQAAMELA KHDAEVQDMA FQYGKHMAMS HKINSDVQPF
IKEKTSDSMT FNLNSAPVVL HQEFLGRDLW IKQIGEAQEK GRLDYAKLRE RIKAGKGVTS
AIDLCRYHGN KALEALESFP PSEARSALEN IVFAVTRFS
//
