ID H2QTL5_PANTR Unreviewed; 680 AA.
AC H2QTL5; A0A2J8PU08;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Collagen type X alpha 1 chain {ECO:0000313|Ensembl:ENSPTRP00000031636.3};
DE SubName: Full=Collagen, type X, alpha 1 {ECO:0000313|EMBL:JAA05187.1};
GN Name=COL10A1 {ECO:0000313|EMBL:JAA05187.1,
GN ECO:0000313|Ensembl:ENSPTRP00000031636.3,
GN ECO:0000313|VGNC:VGNC:10661};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000031636.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000031636.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA05187.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA05187.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000031636.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04054343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01006151; JAA05187.1; -; mRNA.
DR RefSeq; XP_001161595.1; XM_001161595.4.
DR STRING; 9598.ENSPTRP00000031636; -.
DR PaxDb; 9598-ENSPTRP00000031636; -.
DR Ensembl; ENSPTRT00000034229.4; ENSPTRP00000031636.3; ENSPTRG00000018524.4.
DR GeneID; 742603; -.
DR KEGG; ptr:742603; -.
DR CTD; 1300; -.
DR VGNC; VGNC:10661; COL10A1.
DR eggNOG; ENOG502QS5V; Eukaryota.
DR GeneTree; ENSGT00940000154317; -.
DR HOGENOM; CLU_001074_21_0_1; -.
DR OMA; YTYDEYS; -.
DR OrthoDB; 5361230at2759; -.
DR TreeFam; TF334029; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018524; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0005599; C:collagen type X trimer; IEA:Ensembl.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IBA:GO_Central.
DR GO; GO:0030198; P:extracellular matrix organization; IBA:GO_Central.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF33; EMI DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 2: Evidence at transcript level;
KW Collagen {ECO:0000313|EMBL:JAA05187.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..680
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015093065"
FT DOMAIN 547..680
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 56..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..83
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..107
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..148
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..424
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..476
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..519
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 66153 MW; 3EBD89A7B61E95A7 CRC64;
MLPQIPFLLL VSLNLVHGVF YAERYQTPTG IKGPLPNTKT QFFIPYTIKS KGIAVRGEQG
IPGPPGPAGP RGHPGPSGPP GKPGYGSPGL QGEPGLPGPP GPSAVGKPGV PGLPGKPGER
GPYGPKGDVG PAGLPGPRGP PGPPGIPGPA GISVSGKPGQ QGPTGAPGPR GFPGEKGAPG
VPGMNGQKGE MGYGAPGRPG ERGLPGPQGP TGPPGPPGVG KRGENGVPGQ PGIKGDRGFP
GEIGPIGPPG PQGPPGERGP EGIGKPGAAG APGQPGIPGT KGLPGAAGIA GPPGPPGFGK
PGLPGLKGER GPAGLPGGPG AKGEQGPAGL PGKPGLTGPP GNMGPQGPKG IPGNHGLPGP
EGETGPAGPA GYPGAKGERG SPGSDGKPGY PGEPGLDGPK GNPGLPGPKG DPGVGGPPGL
PGPVGPAGAK GMPGHNGEAG PRGAPGIPGT RGPIGPPGIP GFPGSKGDPG SPGPPGPAGI
ATKGLNGPTG PPGPPGPRGH SGEPGLPGPP GPPGPPGQAV MPEGFIKAGQ RPSLSGTPLV
SANQGVTGMP VSAFTVILSK AYPAIGTPIP FDKILYNRQQ HYDPRTGIFT CRIPGIYYFS
YHVHVKGTHV WVGLYKNGTP VMYTYDEYTK GYLDQASGSA IIDLTENDQV WLQLPNAESN
GLYSSEYVHS SFSGFLVAPM
//
