ID H2QUE5_PANTR Unreviewed; 623 AA.
AC H2QUE5; A0A2J8KL54;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Kelch repeat and BTB (POZ) domain containing 2 {ECO:0000313|EMBL:JAA08482.1};
DE SubName: Full=Kelch repeat and BTB domain containing 2 {ECO:0000313|Ensembl:ENSPTRP00000032576.3};
GN Name=KBTBD2 {ECO:0000313|EMBL:JAA08482.1,
GN ECO:0000313|Ensembl:ENSPTRP00000032576.3, ECO:0000313|VGNC:VGNC:8693};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000032576.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000032576.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA08482.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA08482.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA37922.1}, Skin {ECO:0000313|EMBL:JAA27218.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA19755.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000032576.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC148829; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01002856; JAA08482.1; -; mRNA.
DR EMBL; GABF01002390; JAA19755.1; -; mRNA.
DR EMBL; GABD01005882; JAA27218.1; -; mRNA.
DR EMBL; GABE01006817; JAA37922.1; -; mRNA.
DR RefSeq; XP_001167893.1; XM_001167893.5.
DR RefSeq; XP_016801209.1; XM_016945720.1.
DR RefSeq; XP_016801210.1; XM_016945721.1.
DR RefSeq; XP_016801211.1; XM_016945722.1.
DR RefSeq; XP_016801212.1; XM_016945723.1.
DR RefSeq; XP_016812738.1; XM_016957249.1.
DR RefSeq; XP_016812739.1; XM_016957250.1.
DR STRING; 9598.ENSPTRP00000032576; -.
DR PaxDb; 9598-ENSPTRP00000032576; -.
DR Ensembl; ENSPTRT00000035237.4; ENSPTRP00000032576.3; ENSPTRG00000019063.4.
DR Ensembl; ENSPTRT00000090186.1; ENSPTRP00000086763.1; ENSPTRG00000046817.1.
DR Ensembl; ENSPTRT00000108405.1; ENSPTRP00000092915.1; ENSPTRG00000046817.1.
DR GeneID; 463336; -.
DR KEGG; ptr:463336; -.
DR CTD; 25948; -.
DR VGNC; VGNC:8693; KBTBD2.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000156069; -.
DR HOGENOM; CLU_004253_14_5_1; -.
DR OMA; WESRHEM; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF332672; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000019063; Expressed in lymph node and 20 other cell types or tissues.
DR CDD; cd18479; BACK_KBTBD2; 1.
DR CDD; cd18270; BTB_POZ_KBTBD2_BKLHD1; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030586; BTB_POZ_KBTBD2.
DR InterPro; IPR047074; KBTBD2_BACK.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF192; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 31..98
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 623 AA; 71321 MW; B9B4DD28D44A3580 CRC64;
MSTQDERQIN TEYAVSLLEQ LKLFYEQQLF TDIVLIVEGT EFPCHKMVLA TCSSYFRAMF
MSGLSESKQT HVHLRNVDAA TLQIIITYAY TGNLAMNDST VEQLYETACF LQVEDVLQRC
REYLIKKINA ENCVRLLSFA DLFSCEELKQ SAKRMVEHKF TAVYHQDAFM QLSHDLLIDI
LSSDNLNVEK EETVREAAML WLEYNTESRS QYLSSVLSQI RIDALSEVTQ RAWFQGLPPN
DKSVVVQGLY KSMPKFFKPR LGMTKEEMMI FIEASSENSC SLYSSVCYSP QAEKVYKLCS
PPADLHKVGT VVTPDNDIYI AGGQVPLKNT KTNHSKTSKL QTAFRTVNCF YWFDAQQNTW
FPKTPMLFVR IKPSLVCCEG YIYAIGGDSV GGELNRRTVE RYDTEKDEWT MVSPLPCAWQ
WSAAVVVHDC IYVMTLNLMY CYFPRSDSWV EMAMRQTSRS FASAAAFGDK IFYIGGLHIA
TNSGIRLPSG TVDGSSVTVE IYDVNKNEWK MAANIPAKRY SDPCVRAVVI SNSLCVFMRE
THLNERAKYV TYQYDLELDR WSLRQHISER VLWDLGRDFR CTVGKLYPSC LEESPWKPPT
YLFSTDGTEE FELDGEMVAL PPV
//
