ID H2QV12_PANTR Unreviewed; 298 AA.
AC H2QV12; A0A2J8Q0G5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Alpha-2-glycoprotein 1, zinc-binding {ECO:0000313|Ensembl:ENSPTRP00000033312.3};
GN Name=AZGP1 {ECO:0000313|Ensembl:ENSPTRP00000033312.3,
GN ECO:0000313|VGNC:VGNC:14071};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000033312.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000033312.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000033312.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|RuleBase:RU004439}.
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DR EMBL; AC192162; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001143820.1; XM_001143820.5.
DR AlphaFoldDB; H2QV12; -.
DR STRING; 9598.ENSPTRP00000033312; -.
DR PaxDb; 9598-ENSPTRP00000033312; -.
DR Ensembl; ENSPTRT00000036038.4; ENSPTRP00000033312.3; ENSPTRG00000019465.4.
DR GeneID; 737709; -.
DR KEGG; ptr:737709; -.
DR CTD; 563; -.
DR VGNC; VGNC:14071; AZGP1.
DR eggNOG; ENOG502RWW3; Eukaryota.
DR GeneTree; ENSGT01100000263517; -.
DR HOGENOM; CLU_047501_0_1_1; -.
DR InParanoid; H2QV12; -.
DR OMA; APYSCYV; -.
DR OrthoDB; 3840485at2759; -.
DR TreeFam; TF336617; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000019465; Expressed in liver and 12 other cell types or tissues.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IEA:Ensembl.
DR GO; GO:0006955; P:immune response; IBA:GO_Central.
DR CDD; cd21010; IgC1_MHC-like_ZAG; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR PANTHER; PTHR16675:SF276; ZINC-ALPHA-2-GLYCOPROTEIN; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SMART; SM00407; IGc1; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..298
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015093111"
FT DOMAIN 207..292
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 298 AA; 34328 MW; 01DA153A8E32A0B1 CRC64;
MVRMVPVLLS LLLLLGPAVP QENQDGRYSL TYIYTGLSKH VEDVPAFQAL GSLNDLQFFR
YNSKDRKSQP MGLWRQVEGM EDWKQDSQLQ KAREDIFMET LKDIVEYYND SNGSHVLQGR
FGCEIENNRS SGAFWKYYYD GKDYIEFNKE IPAWVPFDPA AQITKQKWEA EPVYVQRAKA
YLEEECPATL RKYLKYSKNI LDRQDPPSVV VTSHQAPGEK KKLKCLAYDF YPGKIDVHWT
RAGEVQEPEL RGDVLHNGNG TYQSWVVVAV PPQDTAPYSC HVQHSSLAQP LVVPWEAR
//
