ID H2QXB0_PANTR Unreviewed; 992 AA.
AC H2QXB0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Ankyrin repeat domain 18A {ECO:0000313|Ensembl:ENSPTRP00000035843.5};
GN Name=ANKRD18A {ECO:0000313|Ensembl:ENSPTRP00000035843.5,
GN ECO:0000313|VGNC:VGNC:4612};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000035843.5, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000035843.5, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000035843.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC186038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016816397.1; XM_016960908.1.
DR RefSeq; XP_520430.3; XM_520430.5.
DR AlphaFoldDB; H2QXB0; -.
DR PaxDb; 9598-ENSPTRP00000035843; -.
DR Ensembl; ENSPTRT00000038773.6; ENSPTRP00000035843.5; ENSPTRG00000020959.6.
DR VGNC; VGNC:4612; ANKRD18A.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000164347; -.
DR HOGENOM; CLU_001111_0_0_1; -.
DR InParanoid; H2QXB0; -.
DR TreeFam; TF333496; -.
DR Proteomes; UP000002277; Chromosome 9.
DR Bgee; ENSPTRG00000020959; Expressed in bone marrow and 17 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039497; CC144C-like_CC_dom.
DR InterPro; IPR021885; DUF3496.
DR PANTHER; PTHR24147; ANKYRIN REPEAT DOMAIN 36-RELATED; 1.
DR PANTHER; PTHR24147:SF22; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18A; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF14915; CCDC144C; 1.
DR Pfam; PF12001; DUF3496; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REPEAT 67..99
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 100..132
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 133..165
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 166..198
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 327..617
FT /note="CCDC144C-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14915"
FT DOMAIN 864..968
FT /note="DUF3496"
FT /evidence="ECO:0000259|Pfam:PF12001"
FT REGION 262..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 377..432
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 774..808
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 834..904
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 276..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 992 AA; 115614 MW; 129CDB0977CB8F9B CRC64;
MRKLFSFGRR LGQALLSSMD QEYAGPGYDI RDWELRKIHR AAIKGDAAEV ERCLTRRFRD
LDARDRKDRT VLHLACAHGR VEVVTLLLHR RCQIDICDRL NRTPLMKAVH GQEEACAILL
LECGANPNIK DIYGNTALHY AVYNKGTSLA ERLLSHHANI EALNKEGNTP LLFAINSRRQ
HMVEFLLKNQ ANIHAVDNFK RTALILAVQH NLSSIVTLLL QQNIRISSQD MFGQTAEDYA
FCCDLRSIRQ QILEHKNKML KNHLRNDNQE TAAMKPANMK KRKERAKAEQ NLKVASEEKQ
ERLERSENKQ PQDSQSYGKK KDAMYGNFML KRDIAMLKEE LYAIKNDSLR KENKYIQEIK
SITEINAKFE KSVRLNEEMI TKKVAQYSQQ LNDLKAENAR LNSELEKEKH NKERLEAEVE
SLHSNLATAI NEYNEIVERK DLELVLRRAD DVSRHEKMGS NISKLTDKNE LLTEQVHKAR
VKFNTLKGKL RETRDALREK TLALGSVQLD LRQAQHRIKE MKQMHPNGEA KESQSIGKQN
SLEERIRQRE LENLLLERQL EDARKEGDNK EIVINIHRDC LENGKEDLLE ERNKELMKEY
NYLKEKLLQY EKEKAEREVI VRECQEELVD HLKKFSNSES PLEGTSHCHI NLDETWTSKK
KLFQVEIQPE EKHEEFRKLF ELISLLNYTA DQIRKKNREL EEEATGSKKC LEMTINMLNA
FANEDFSCHG DLNTDQLKMD ILFKKLKQKF NDLVAEKEAV SSKCVNLAKD NEVLHQELLS
MRKVQEKCEK LEKDKKMLEE EVLNLKTHME KDMVELGKLQ EYKSELDERA VQEIEKLEEI
HLQKQAEYEK QLEQLNKDNT ASLKKKELTL KDVECKFSKM KTAYEEVTTE LEEFKEAFAA
ALKANNSMSK KLTKSDKKIA VISTKLFTEK QRMKYFLSTL PTRPEPELPC VENLNSIELN
RKYIPKTAIR IPTSNPQTSN NCKNSLTEVL LC
//
