ID H2QZF9_PANTR Unreviewed; 509 AA.
AC H2QZF9; A0A2J8KUI0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=MSL complex subunit 3 {ECO:0000313|Ensembl:ENSPTRP00000038929.4};
GN Name=MSL3 {ECO:0000313|Ensembl:ENSPTRP00000038929.4,
GN ECO:0000313|VGNC:VGNC:56328};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000038929.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000038929.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000038929.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AACZ04014646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC195292; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001144354.1; XM_001144354.4.
DR AlphaFoldDB; H2QZF9; -.
DR SMR; H2QZF9; -.
DR Ensembl; ENSPTRT00000049748.4; ENSPTRP00000038929.4; ENSPTRG00000021662.6.
DR GeneID; 465491; -.
DR KEGG; ptr:465491; -.
DR CTD; 10943; -.
DR VGNC; VGNC:56328; MSL3.
DR eggNOG; KOG3001; Eukaryota.
DR GeneTree; ENSGT00950000182965; -.
DR HOGENOM; CLU_039566_5_2_1; -.
DR OrthoDB; 2878816at2759; -.
DR TreeFam; TF323400; -.
DR Proteomes; UP000002277; Chromosome X.
DR Bgee; ENSPTRG00000021662; Expressed in thymus and 21 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 2.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF15; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51640; MRG; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 21..78
FT /note="Chromo"
FT /evidence="ECO:0000259|SMART:SM00298"
FT REGION 101..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..141
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..345
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 509 AA; 58249 MW; 50F8B10061D5E89E CRC64;
MSPSVRPGAG WAPVGRPGRP IQIVDVIVGK DEKGRKIPEY LIHFNGWNRS WDRWAAEDHV
LRDTDENRRL QRKLARKAVA RLRSTGRKKK RCRLPGVDSV LKGLPTEEKD ENDENSLSSS
SDCSENKDEE ISEESDIEEK TEVKEEPELQ TRREMEERTI TIEIPEVLKK QLEDDCYYIN
RRKRLVKLPC QTNIITILES YVKHFAINAA FSANERPRHH HVMPHANMNV HYIPAEKNVD
LCKEMVDGLR ITFDYTLPLV LLYPYEQAQY KKVTSSKFFL PIKESATSTN RSQEELSPSP
PLLNPSTPQS TESQPTTGEP ATPKRRKAEP EALQSLRRST RHSANCDRLS ESSASPQPKR
RQQDTSASMP KLFLHLEKKT PVHSRSSSPI PLTPSKEGSA VFAGFEGRRT NEINEVLSWK
LVPDNYPPGD QPPPPSYIYG AQHLLRLFVK LPEILGKMSF SEKNLKALLK HFDLFLRFLA
EYHDDFFPES AYVAACEAHY STKNPRAIY
//
