ID H2R0G1_PANTR Unreviewed; 503 AA.
AC H2R0G1; A0A2J8PR35;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=WAS/WASL interacting protein family member 1 {ECO:0000313|Ensembl:ENSPTRP00000040676.3};
DE SubName: Full=WAS/WASL interacting protein family, member 1 {ECO:0000313|EMBL:JAA13239.1};
GN Name=WIPF1 {ECO:0000313|EMBL:JAA13239.1,
GN ECO:0000313|Ensembl:ENSPTRP00000040676.3, ECO:0000313|VGNC:VGNC:3877};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000040676.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000040676.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA13239.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA44012.1}, Skin
RC {ECO:0000313|EMBL:JAA31212.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA13239.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000040676.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04058539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABF01008906; JAA13239.1; -; mRNA.
DR EMBL; GABD01001888; JAA31212.1; -; mRNA.
DR EMBL; GABE01000727; JAA44012.1; -; mRNA.
DR RefSeq; XP_001150625.1; XM_001150625.5.
DR RefSeq; XP_009442065.1; XM_009443790.2.
DR RefSeq; XP_009442066.1; XM_009443791.2.
DR RefSeq; XP_009442067.1; XM_009443792.2.
DR STRING; 9598.ENSPTRP00000075263; -.
DR PaxDb; 9598-ENSPTRP00000040676; -.
DR Ensembl; ENSPTRT00000042913.4; ENSPTRP00000040676.3; ENSPTRG00000012656.7.
DR GeneID; 459755; -.
DR KEGG; ptr:459755; -.
DR CTD; 7456; -.
DR VGNC; VGNC:3877; WIPF1.
DR eggNOG; KOG4462; Eukaryota.
DR GeneTree; ENSGT00940000167313; -.
DR HOGENOM; CLU_041032_0_0_1; -.
DR OMA; EPQRSRM; -.
DR OrthoDB; 5324507at2759; -.
DR TreeFam; TF332135; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000012656; Expressed in lymph node and 20 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0030029; P:actin filament-based process; IEA:UniProt.
DR CDD; cd22076; WH2_WAS_WASL-1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR48226; OS06G0326200 PROTEIN; 1.
DR PANTHER; PTHR48226:SF1; WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1; 1.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00246; WH2; 1.
DR PROSITE; PS51082; WH2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 32..49
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..192
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..224
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..326
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..387
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..436
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 51220 MW; C1B3C42AABBBA7E8 CRC64;
MPVPPPPAPP PPPTFALANT EKPTLNKTEQ AGRNALLSDI SKGKKLKKTV TNDRSAPILD
KPKGAGAGGG GGGFGGGGGF GGGGGGGGGG SFGGGGPPGL GGLFQAGMPK LRSTANRDND
SGGSRPPLLP PGGRSTSAKP FSPPSGPGRF PVPSAGHRSG PPEPQRNRMP PPRPDVGSKP
DSIPPPVPST PRPIQSSLHN RGSPPVPGGP RQPSPGPTPP PFPGNRGTAL GGGSIRQSPL
SSSSPFSNRP PLPPTPSRAL DDKPPPPPPP VGNRPSIHRE AVPPPPPQNN KPPVPSTPRP
SASSQAPPPP PPPSRPGPPP LPPSSSGNDE TPRLPQRNLS LSSSTPPLPS PGRSGPLPPP
PSERPPPPVR DPPGRSGPLP PPPPASRNGS TSRALPATPQ LPSRSGVDSP RSGPRPPLPP
DRPSAGAPPP PPPSTSIRNG FQDSPCEDEW ESRFYFHPIS DLPPPEPYVQ TTKSYPSKLA
RNESRSGSNR RERGAPPLPP IPR
//
