ID H2R0L3_PANTR Unreviewed; 403 AA.
AC H2R0L3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Dynactin subunit 2 {ECO:0000256|ARBA:ARBA00034866};
GN Name=DCTN2 {ECO:0000313|Ensembl:ENSPTRP00000040891.5,
GN ECO:0000313|VGNC:VGNC:5354};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000040891.5, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000040891.5, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000040891.5}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynactin subunit 2 family.
CC {ECO:0000256|ARBA:ARBA00006176}.
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DR EMBL; AC191734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2R0L3; -.
DR Ensembl; ENSPTRT00000044815.5; ENSPTRP00000040891.5; ENSPTRG00000005138.6.
DR VGNC; VGNC:5354; DCTN2.
DR eggNOG; KOG3958; Eukaryota.
DR GeneTree; ENSGT00390000003427; -.
DR HOGENOM; CLU_049964_1_0_1; -.
DR TreeFam; TF105247; -.
DR Proteomes; UP000002277; Chromosome 12.
DR Bgee; ENSPTRG00000005138; Expressed in Brodmann (1909) area 10 and 20 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR InterPro; IPR028133; Dynamitin.
DR PANTHER; PTHR15346; DYNACTIN SUBUNIT; 1.
DR PANTHER; PTHR15346:SF0; DYNACTIN SUBUNIT 2; 1.
DR Pfam; PF04912; Dynamitin; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 105..132
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 44529 MW; 399D38E3962FCD1A CRC64;
MGQESCRTME KGIEARNEPD VYETSDLPED DQAEFDAEEL TSTSVEHIIV NPNAAYDKFK
DKRVGTKGLD FSDRIGKTKR TGYESGEYEM LGEGLGVKET PQQKYQRLLH EVQELTTEVE
KIKTTVKESA TEEKLTSVLL AKQLAALKQQ LVASHLEKLL GPDAAINLTD PDGALAKRLL
LQLEATKNSK GGSGGKTTGT PPDSSLVTYE LHSRPEQDKF SQAAKVAELE KRLTELETAV
RCDQDAQNPL SAGLQGACLM ETVELLQAKV SALDLAVLDQ VEARLQSVLG KVNEIAKHKA
SVEDADTQSK VHQLYETIQR WSPIASTLPE LVQRLVTIKQ LHEQAMQFGQ LLTHLDTTQQ
MIANSLKDNT TLLTQVQTTM RENLATVEGN FASIDERMKK LGK
//
