ID H2R396_PANTR Unreviewed; 207 AA.
AC H2R396; A0A2J8KK46;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=FGF16 {ECO:0000313|Ensembl:ENSPTRP00000045123.2,
GN ECO:0000313|VGNC:VGNC:12344};
GN Synonyms=FGF4C {ECO:0000313|EMBL:VDK10852.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000045123.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000045123.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:VDK10852.1}
RP NUCLEOTIDE SEQUENCE.
RA Premzl M.;
RT "Comparative genomic analysis of eutherian fibroblast growth factor
RT genes.";
RL BMC Genomics 21:542-542(2020).
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000045123.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR EMBL; AACZ04026365; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; LR130272; VDK10852.1; -; Genomic_DNA.
DR RefSeq; XP_529049.2; XM_529049.4.
DR STRING; 9598.ENSPTRP00000045123; -.
DR PaxDb; 9598-ENSPTRP00000045123; -.
DR Ensembl; ENSPTRT00000042612.3; ENSPTRP00000045123.2; ENSPTRG00000022533.3.
DR GeneID; 473676; -.
DR KEGG; ptr:473676; -.
DR CTD; 8823; -.
DR VGNC; VGNC:12344; FGF16.
DR eggNOG; KOG3885; Eukaryota.
DR GeneTree; ENSGT00940000160087; -.
DR HOGENOM; CLU_081609_0_0_1; -.
DR OMA; MDSERHY; -.
DR OrthoDB; 2883843at2759; -.
DR TreeFam; TF317805; -.
DR Proteomes; UP000002277; Chromosome X.
DR Bgee; ENSPTRG00000022533; Expressed in heart and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005104; F:fibroblast growth factor receptor binding; IBA:GO_Central.
DR GO; GO:0008083; F:growth factor activity; IBA:GO_Central.
DR GO; GO:0009887; P:animal organ morphogenesis; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IBA:GO_Central.
DR GO; GO:2000546; P:positive regulation of endothelial cell chemotaxis to fibroblast growth factor; IBA:GO_Central.
DR GO; GO:0010628; P:positive regulation of gene expression; IBA:GO_Central.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IBA:GO_Central.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF27; FIBROBLAST GROWTH FACTOR 16; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 207 AA; 23759 MW; D8AD160BDABDB5F8 CRC64;
MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL
RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER
GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH
QKFTHFLPRP VDPSKLPSMS RDLFHYR
//
