ID H2R3D6_PANTR Unreviewed; 280 AA.
AC H2R3D6; A0A2J8KJY0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=High mobility group nucleosome binding domain 5 {ECO:0000313|Ensembl:ENSPTRP00000045332.2};
GN Name=HMGN5 {ECO:0000313|Ensembl:ENSPTRP00000045332.2,
GN ECO:0000313|VGNC:VGNC:12403};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000045332.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000045332.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000045332.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HMGN family.
CC {ECO:0000256|ARBA:ARBA00007696}.
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DR EMBL; AC193679; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001144951.2; XM_001144951.4.
DR AlphaFoldDB; H2R3D6; -.
DR STRING; 9598.ENSPTRP00000045332; -.
DR PaxDb; 9598-ENSPTRP00000045332; -.
DR Ensembl; ENSPTRT00000043448.3; ENSPTRP00000045332.2; ENSPTRG00000022527.4.
DR GeneID; 465732; -.
DR KEGG; ptr:465732; -.
DR CTD; 79366; -.
DR VGNC; VGNC:12403; HMGN5.
DR eggNOG; ENOG502QQGX; Eukaryota.
DR GeneTree; ENSGT00730000111570; -.
DR HOGENOM; CLU_082746_0_0_1; -.
DR InParanoid; H2R3D6; -.
DR OMA; EYNNENA; -.
DR OrthoDB; 4841811at2759; -.
DR Proteomes; UP000002277; Chromosome X.
DR Bgee; ENSPTRG00000022527; Expressed in testis and 20 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0031492; F:nucleosomal DNA binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:InterPro.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR InterPro; IPR040164; HMGN5.
DR InterPro; IPR000079; HMGN_fam.
DR PANTHER; PTHR23145:SF6; HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR23145; NUCLEOSOMAL BINDING PROTEIN 1; 1.
DR Pfam; PF01101; HMG14_17; 1.
DR PRINTS; PR00925; NONHISHMG17.
DR SMART; SM00527; HMG17; 1.
DR PROSITE; PS00355; HMG14_17; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 1..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 280 AA; 31638 MW; AA975DE6B82048B5 CRC64;
MPKRKAAGQG DMRQEPKRRS ARLSAMLVPV TPEVKPKRTS SSRKMKTKSD MMEENIDTSA
QAVAETKQEA VVEEDYNENA KNGEAKITEA PASEKEIVEV KEENIEDATE KGGEKKEAVA
AEVKNEEEDQ KEDEEDQNEE KGEARKEDKD EKGEEDGKED KNGNEKGEDA KEKEDGKKGE
DGKGNGEDEK EEEDRKETGD GKENEDGKEK GDKKEEKDVK VKEDEKERED GKEDEGGNEE
EAGKEKEDLK EERKEEEEEG KEEDEIEEEN GKKEEPQSIV
//
