ID H2R3I1_PANTR Unreviewed; 237 AA.
AC H2R3I1; A0A2J8P7K5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Potassium channel tetramerisation domain containing 6 {ECO:0000313|EMBL:JAA01212.1};
DE SubName: Full=Potassium channel tetramerization domain containing 6 {ECO:0000313|Ensembl:ENSPTRP00000045548.4};
GN Name=KCTD6 {ECO:0000313|EMBL:JAA01212.1,
GN ECO:0000313|Ensembl:ENSPTRP00000045548.4,
GN ECO:0000313|VGNC:VGNC:11420};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000045548.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000045548.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA01212.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA01212.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA42971.1}, Skin {ECO:0000313|EMBL:JAA23103.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA19531.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000045548.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04000359; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01010126; JAA01212.1; -; mRNA.
DR EMBL; GABF01002614; JAA19531.1; -; mRNA.
DR EMBL; GABD01009997; JAA23103.1; -; mRNA.
DR EMBL; GABE01001768; JAA42971.1; -; mRNA.
DR RefSeq; XP_001174242.1; XM_001174242.4.
DR RefSeq; XP_009444004.1; XM_009445729.2.
DR RefSeq; XP_526216.2; XM_526216.6.
DR STRING; 9598.ENSPTRP00000045548; -.
DR PaxDb; 9598-ENSPTRP00000045548; -.
DR Ensembl; ENSPTRT00000043740.5; ENSPTRP00000045548.4; ENSPTRG00000015060.6.
DR GeneID; 470833; -.
DR KEGG; ptr:470833; -.
DR CTD; 200845; -.
DR VGNC; VGNC:11420; KCTD6.
DR eggNOG; KOG2723; Eukaryota.
DR GeneTree; ENSGT00940000157869; -.
DR HOGENOM; CLU_070345_1_0_1; -.
DR OMA; WGYIMTE; -.
DR OrthoDB; 2912088at2759; -.
DR TreeFam; TF315332; -.
DR Proteomes; UP000002277; Chromosome 3.
DR Bgee; ENSPTRG00000015060; Expressed in cerebellar cortex and 20 other cell types or tissues.
DR GO; GO:0030506; F:ankyrin binding; IEA:Ensembl.
DR GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd18394; BTB_POZ_KCTD6; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR PANTHER; PTHR14499:SF10; BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD6; 1.
DR PANTHER; PTHR14499; POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING; 1.
DR Pfam; PF02214; BTB_2; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
PE 2: Evidence at transcript level;
KW Ion channel {ECO:0000313|EMBL:JAA01212.1};
KW Ion transport {ECO:0000313|EMBL:JAA01212.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transport {ECO:0000313|EMBL:JAA01212.1}.
FT DOMAIN 12..113
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
SQ SEQUENCE 237 AA; 27610 MW; 6358D9993DD060ED CRC64;
MDNGDWGYMM TDPVTLNVGG HLYTTSLTTL TRYPDSMLGA MFGGDFPTAR DPQGNYFIDR
DGPLFRYVLN FLRTSELTLP LDFKEFDLLR KEADFYQIEP LIQCLNDPKP LYPMDTFEEV
VELSSTRKLS KYSNPVAVII TQLTITTKVH SLLEGISNYF TKWNKHMMDT RDCQVSFTFG
PCDYHQEVSL RVHLMEYITK QGFTIRNTRV HHMSERANEN TVEHNWTFCR LARKTDD
//
