ID H2R569_PANTR Unreviewed; 437 AA.
AC H2R569; A0A2J8QAQ4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN Name=CHKA {ECO:0000313|Ensembl:ENSPTRP00000047873.3,
GN ECO:0000313|VGNC:VGNC:11297};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000047873.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000047873.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000047873.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; AACZ04016236; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04016237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04016238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC183808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2R569; -.
DR Ensembl; ENSPTRT00000007426.5; ENSPTRP00000047873.3; ENSPTRG00000003980.6.
DR VGNC; VGNC:11297; CHKA.
DR eggNOG; KOG2686; Eukaryota.
DR GeneTree; ENSGT00950000182939; -.
DR HOGENOM; CLU_012712_2_1_1; -.
DR OMA; IETSIDY; -.
DR TreeFam; TF313549; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003980; Expressed in testis and 20 other cell types or tissues.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603:SF36; CHOLINE KINASE ALPHA; 1.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 1..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..79
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 49924 MW; C0AAC90915EEDE98 CRC64;
MKTKFCTGGE AEPSPLGLLL SCGSGSAASA PGVGQQRDAA SDLESKQLGG QQPPLALPPP
PPLPLPLPQS PPPQPPADEQ PEPRTRRRAY LWCKEFLPGA WRGLREDEFH ISVIRGGLSN
MLFQCSLPDT TATLGDEPRK VLLRLYGAIL QMGAEAMVLE SVMFAILAER SLGPKLYGIF
PQGRLEQFIP SRRLDTEELS LPDISAEIAE KMATFHGMKM PFNKEPKWLF GTMEKYLKEV
LRIKFTEESR IKKLHKLLSY NLPLELENLR SLLESTPSPV VFCHNDCQEG NILLLEGREN
SEKQKLMLID FEYSSYNYRG FDIGNHFCEW MYDYSYEKYP FFRANIRKYP TKKQQLHFIS
SYLPAFQNDF ENLSTEEKSI IKEEMLLEVN RFALASHFLW GLWSIVQAKI SSIEFGYMDY
AQARFDAYFH QKRKLGV
//
