ID H2RAV9_PANTR Unreviewed; 375 AA.
AC H2RAV9; A0A2J8MKZ1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Protein NDRG3 {ECO:0000256|ARBA:ARBA00015425};
DE AltName: Full=N-myc downstream-regulated gene 3 protein {ECO:0000256|ARBA:ARBA00030207};
GN Name=NDRG3 {ECO:0000313|EMBL:JAA01613.1,
GN ECO:0000313|Ensembl:ENSPTRP00000054588.2, ECO:0000313|VGNC:VGNC:6207};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000054588.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000054588.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA01613.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA01613.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA36314.1}, Skin {ECO:0000313|EMBL:JAA26308.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA18864.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000054588.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NDRG family.
CC {ECO:0000256|ARBA:ARBA00005598}.
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DR EMBL; AACZ04052777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04052778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04052779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04052780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01009725; JAA01613.1; -; mRNA.
DR EMBL; GABF01003281; JAA18864.1; -; mRNA.
DR EMBL; GABF01003280; JAA18865.1; -; mRNA.
DR EMBL; GABF01003279; JAA18866.1; -; mRNA.
DR EMBL; GABD01006792; JAA26308.1; -; mRNA.
DR EMBL; GABD01006791; JAA26309.1; -; mRNA.
DR EMBL; GABD01006790; JAA26310.1; -; mRNA.
DR EMBL; GABE01008425; JAA36314.1; -; mRNA.
DR RefSeq; XP_001138768.1; XM_001138768.3.
DR ESTHER; pantr-h2rav9; Ndr_family.
DR MEROPS; S33.987; -.
DR PaxDb; 9598-ENSPTRP00000054588; -.
DR Ensembl; ENSPTRT00000062037.3; ENSPTRP00000054588.2; ENSPTRG00000013462.7.
DR GeneID; 735544; -.
DR KEGG; ptr:735544; -.
DR CTD; 57446; -.
DR VGNC; VGNC:6207; NDRG3.
DR eggNOG; KOG2931; Eukaryota.
DR GeneTree; ENSGT00950000182872; -.
DR HOGENOM; CLU_035361_1_0_1; -.
DR OrthoDB; 5352016at2759; -.
DR TreeFam; TF313168; -.
DR Proteomes; UP000002277; Chromosome 20.
DR Bgee; ENSPTRG00000013462; Expressed in primary visual cortex and 21 other cell types or tissues.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR004142; NDRG.
DR PANTHER; PTHR11034; N-MYC DOWNSTREAM REGULATED; 1.
DR PANTHER; PTHR11034:SF20; PROTEIN NDRG3; 1.
DR Pfam; PF03096; Ndr; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 326..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 41409 MW; 237B6DF43AAB7F1E CRC64;
MDELQDVQLT EIKPLLNDKN GTRNFQDFDC QEHDIETTHG VVHVTIRGLP KGNRPVILTY
HDIGLNHKSC FNAFFNFEDM QEITQHFAVC HVDAPGQQEG APSFPTGYQY PTMDELAEML
PPVLTHLSLK SIIGIGVGAG AYILSRFALN HPELVEGLVL INVDPCAKGW IDWAASKLSG
LTTNVVDIIL AHHFGQEELQ ANLDLIQTYR MHIAQDINQD NLQLFLNSYN GRRDLEIERP
ILGQNDNKSK TLKCSTLLVV GDNSPAVEAV VECNSRLNPI NTTLLKMADC GGLPQVVQPG
KLTEAFKYFL QGMGYIPSAS MTRLARSRTH STSSSLGSGE SPFSRSVTSN QSDGTQESCE
SPDVLDRHQT MEVSC
//
