ID H2RCR6_PANTR Unreviewed; 1895 AA.
AC H2RCR6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Obscurin like cytoskeletal adaptor 1 {ECO:0000313|Ensembl:ENSPTRP00000057729.2};
GN Name=OBSL1 {ECO:0000313|Ensembl:ENSPTRP00000057729.2,
GN ECO:0000313|VGNC:VGNC:14328};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000057729.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000057729.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000057729.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC158240; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003309516.1; XM_003309468.3.
DR PaxDb; 9598-ENSPTRP00000057729; -.
DR Ensembl; ENSPTRT00000066153.3; ENSPTRP00000057729.2; ENSPTRG00000012963.6.
DR GeneID; 459967; -.
DR KEGG; ptr:459967; -.
DR CTD; 23363; -.
DR VGNC; VGNC:14328; OBSL1.
DR eggNOG; KOG0613; Eukaryota.
DR GeneTree; ENSGT00940000156702; -.
DR HOGENOM; CLU_000630_0_0_1; -.
DR InParanoid; H2RCR6; -.
DR OrthoDB; 4633043at2759; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000012963; Expressed in cerebellar cortex and 20 other cell types or tissues.
DR GO; GO:1990393; C:3M complex; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:Ensembl.
DR GO; GO:0007088; P:regulation of mitotic nuclear division; IEA:Ensembl.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 2.
DR CDD; cd04979; Ig_Semaphorin_C; 1.
DR CDD; cd20967; IgI_C2_MyBP-C-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 20.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR35971:SF6; OBSCURIN-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR35971; SI:DKEY-31G6.6; 1.
DR Pfam; PF07679; I-set; 14.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 18.
DR SMART; SM00408; IGc2; 14.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 18.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 15.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 12..100
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 128..224
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 242..329
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 338..424
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 516..614
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 713..799
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 803..890
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 901..981
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 985..1074
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1077..1162
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1175..1260
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1264..1342
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1358..1442
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1446..1533
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1627..1712
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1793..1895
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 106..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1895 AA; 207032 MW; 323F6120E70B0A1F CRC64;
MKASSGDQGS PPCFLRFPRP VRVVSGAEAE LKCVVLGEPP PVVVWEKGGQ QLAASERLSF
PADGAEHGLL LSAALPTDAG VYVCRARNAA GEAYAAAAVT VLEPPASDPE LQPAERPLPS
PGSGEGAPVF LTGPRSQWVL RGAEVVLTCR AGGLPEPTLY WEKDGMALDE VWDSSHFALE
QGLEDGPGAS LALRILAARL PDSGVYVCHA RNAHGHAQAG ALLQVHQPPE SPPADPDEAP
APVVEPLKCA PKTFWVNEGK HAKFRCYVMG KPEPEIEWHW EGRPLLPDRR RLMYRDRDGG
FVLKVLYCQA KDRGLYVCAA RNSAGQTLSA VQLHVKEPRL RFTRPLQDVE GREHGIAVLE
CKVPNSRIPT AWFREDQRLL PCRKYEQIEE GTVRRLIIHR LKADDDGIYL CEMRGRVRTV
ANVTVKGPIL KRLPRKLDVL EGENAVLLVE TLEAGVEGRW SRDGEELPVI CQSSSGHMHA
LVLPGVTRED AGEVTFSLGN SRTTTLLRVK CVKHSPPGPP ISAEMFKGHK NTVLLTWKPP
EPAPETPFIY RLERQEVGSE DWIQCFSIEK AGAVEVPGDC VPSEGDYRFR ICTVSGHGRS
PHVVFHGSAH LVPTARLVAG LEDVQVYDGE DAVFSLDLST IIQGTWFLNG EELKSNEPEG
QVEPGALRYC MEQKGLQHRL ILHAVKHQDS GALVGFSCPG VQDSAALTIQ ESPVHILSPQ
DKVSLTFTTS ERVVLTCELS RVDFPATWYK DGQKVEDSEL LVVKMDGRKH RLILPEAKVQ
DSGEFECRTE GVSAFFGVTV QDPPVHIVDP REHVFVHAIT SECVMLACEV DREDAPVRWY
KDGQEVEESD FVVLENEGPH RRLVLPATQP SDGGEFQCVA GDERAYFTVT ITDVSSWIVY
PSGKVYVAAV RLERVVLTCE LCRPWAEVRW TKDGEEVVES PALLLQKEDT VRRLVLPAVQ
LEDSGEYLCE IDDESASFTV TVTEPPVRII YPRDEVTLIA VTLECVVLMC ELSREDAPVR
WYKDGLEVEE SEALVLERDG PRCRLVLPAA QPEDGGEFVC DAGDDSAFFT VTVTAPPERI
VHPAARSLDL HFGAPGRVEL RCEVAPAGSQ VRWYKDGLEV EASDALQLGA EGPTRTLTLP
HAQPEDAGEY VCETRDEAIT FNVILAEPPV QFLAPETTPS PLCVAPGEPV VLSCELSRAG
APVVWSHNGR PVQEGEGLEL HAEGPRRVLC IQAAGPAHAG LYTCQSGAAP GAPSLSFTVQ
VAEPPVRVVA PEAAQTRVRS TPGGDLELVV HLSGPGGPVR WYKDGERLAS QGRVQLEQAG
ARQVLRVQGA RSRDAGEYLC DAPQDSRIFL VSVEEPLPVK LVSELTPLTV HEGDDATFRC
EVSPPDADVT WLRNGAVVTP GPQAEMAQNG SSRILTLRGC QLGDAGTVTV RAGITATSAR
LHVRETELLF LRRLQDVRAE EGQDVCLEVE TGRVGTAGAV RWVRGGQPLP HDSRLSMAQD
GHIHRLFIHG VILADQGTYG CESHHDRTLA RLSVRPRQLR VLRPLEDVTI SEGGSATFQL
ELSQEGVTGE WARGGVRLYP GPKCHIHSDG HRHRLVLNSL GLADSGCVSF TADSLRCAAR
LIVREVPVTI VRGPHDLEVT EGDTATFECE LSQALADVTW EKDGSALTPS PRLWLQALGT
RRLLQLRRCG PSDAGTYSCA VGTARARPVR LTVRERTVAV LSELRSVSAR EGDGATFECT
VSEVEITGRW ELGGRPLRPG ARVRIRQEGK KHILVLSELR AEDAGEVRFQ AGPAQSLALL
EVEALPLQMC RHPPREKTVL VGRRAVLEVT VSRSGGHVCW LREGAELCPG DKYEMRSHGP
THSLVIHDVR PEDQGTYCCQ AGQDSTHTRL LVEGN
//
