ID H2RGI7_PANTR Unreviewed; 610 AA.
AC H2RGI7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Schlafen family member 12 like {ECO:0000313|Ensembl:ENSPTRP00000060634.2};
GN Name=SLFN12L {ECO:0000313|Ensembl:ENSPTRP00000060634.2,
GN ECO:0000313|VGNC:VGNC:9630};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000060634.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000060634.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000060634.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC157480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2RGI7; -.
DR PaxDb; 9598-ENSPTRP00000060634; -.
DR Ensembl; ENSPTRT00000075366.2; ENSPTRP00000060634.2; ENSPTRG00000030902.4.
DR VGNC; VGNC:9630; SLFN12L.
DR eggNOG; ENOG502RU3F; Eukaryota.
DR GeneTree; ENSGT00410000025651; -.
DR HOGENOM; CLU_034558_0_0_1; -.
DR InParanoid; H2RGI7; -.
DR TreeFam; TF337168; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000030902; Expressed in spleen and 7 other cell types or tissues.
DR Gene3D; 3.30.950.30; Schlafen, AAA domain; 1.
DR InterPro; IPR031450; Poxin-SLFN/SLFN_N.
DR InterPro; IPR029684; Schlafen.
DR InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR InterPro; IPR048729; SLFN_GTPase-like.
DR PANTHER; PTHR12155; SCHLAFEN; 1.
DR PANTHER; PTHR12155:SF46; SCHLAFEN FAMILY MEMBER 12-LIKE; 1.
DR Pfam; PF17057; B3R; 1.
DR Pfam; PF04326; SLFN_AlbA_2; 1.
DR Pfam; PF21026; SLFN_GTPase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 124..240
FT /note="Poxin-Schlafen/Schlafen-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17057"
FT DOMAIN 242..356
FT /note="Schlafen AlbA-2"
FT /evidence="ECO:0000259|Pfam:PF04326"
FT DOMAIN 432..569
FT /note="Schlafen GTPase-like"
FT /evidence="ECO:0000259|Pfam:PF21026"
SQ SEQUENCE 610 AA; 69395 MW; DDF6C576359B5DCD CRC64;
MQLSEGAGKW KRTQVPLLGE ECADMDLARK EFLRGNGLAA GKMNISIDLD TNYAELVLNV
GRVTLGENNR KKMKDCQLRK QQNENVSRAV CALLNSGGGF IKAEVENKGY SYKKDGIGLD
LENSFSNMLP FVPNFLDFMQ NGNYFHIFVK SWSLETSGPQ TATLSSSLYK RDVTSAKVMN
ASAALEFLKD MEKTGGRAYL RPEFPAKRAC VDVQEESNME ALAADFFNRT ELGYKEKLTF
TESTHVEIKN FSTEKLLQRI TEILPQYVSA FANTDGGYLF VGINEDKEII GFKAEKSYLT
KLEEVTKNSI GKLPVHHFCV EKGTINYLCK FLGVYDKGRL CGYVYALRVE RFCCAVFAKK
PDSWHVKDNR VKQLTEKEWI QFMVDSEPVW EELPSPASTS SLVSLVSQSC RLREYINFKI
QPLRYHLPGL SEKITCAPKT FCRNLFSQHE GLKQLICEEM GSVSKGSLIF SRSWSLDLGL
QENHKVLCDA LLISQDKPPV LYTFHMVQDE EFKDCSTQTA QTLKQKLAKI GGYTKKVCVM
TKIFYLSPEG KTSCQYDLNS QVIYPESYYW TTAQTMKDLE KALSNILPKE NQIFLFVCLC
LIKYYMKMYS
//
