ID H2RMA5_TAKRU Unreviewed; 485 AA.
AC H2RMA5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 {ECO:0000313|Ensembl:ENSTRUP00000001268.2};
GN Name=enpp5 {ECO:0000313|Ensembl:ENSTRUP00000001268.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000001268.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000001268.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000001268.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003976195.1; XM_003976146.2.
DR AlphaFoldDB; H2RMA5; -.
DR STRING; 31033.ENSTRUP00000001268; -.
DR Ensembl; ENSTRUT00000001274.3; ENSTRUP00000001268.2; ENSTRUG00000000539.3.
DR GeneID; 101070940; -.
DR KEGG; tru:101070940; -.
DR CTD; 59084; -.
DR GeneTree; ENSGT00940000160562; -.
DR HOGENOM; CLU_017594_1_2_1; -.
DR InParanoid; H2RMA5; -.
DR OMA; DEYVSRD; -.
DR OrthoDB; 1366859at2759; -.
DR Proteomes; UP000005226; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0047710; F:bis(5'-adenosyl)-triphosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd16018; Enpp; 1.
DR Gene3D; 3.30.1360.180; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR10151:SF125; ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 5; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..485
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017396936"
FT TRANSMEM 436..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 485 AA; 54996 MW; BFD64741E64ACA3B CRC64;
MSCTMLRWLL RGGCRPLVGL WALLLPVVSS HGLQQDALTE GRPKLLLVSF DGFRWDYVDR
VPMPNFFSIM NDGVMVKQVE NIYITKTFPN HYTLVTGLYA ETHGIVANEM FDPVLNRSFS
IETETMYDPQ WWEEAVPLWV SIQKAGGRSG AAMWPGSDVK IRGVFPNQFL RYNASVPFET
RVERIIQWFS APKEEAVDFG VLYWEDPDKS GHLLGPQSLL MDAVIAGIDE KLGFLMNELK
KAGIYEKVNL IVTSDHGMVQ LSPDHIIELD EYVSRDLYTW VDKSPVVGIL PKEGKLDEVY
SKLVDANPNM MVYKKESIPA HFHYQHNSRI MPILLEAKEG WTIMQNRSGT FLLGNHGNDN
TLPSMHPVFI ARGPAFRQNY VKSFMRSVDL YPLMCHILSI PALPNNGSLS NVKDLLLREP
TPTVPSARLR VKDNSYAPLV GSLMGVAMVL GFLVVFIKQV TLKQLPSLKH RRREMSQPLL
QDLHL
//
