ID H2RR04_TAKRU Unreviewed; 856 AA.
AC H2RR04;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=PHD finger protein 14 {ECO:0000313|Ensembl:ENSTRUP00000002570.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000002570.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000002570.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000002570.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2RR04; -.
DR Ensembl; ENSTRUT00000002582.3; ENSTRUP00000002570.3; ENSTRUG00000001101.3.
DR eggNOG; KOG0957; Eukaryota.
DR GeneTree; ENSGT00940000156923; -.
DR HOGENOM; CLU_006506_0_0_1; -.
DR TreeFam; TF316118; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15674; ePHD_PHF14; 1.
DR CDD; cd15561; PHD1_PHF14; 1.
DR CDD; cd15562; PHD2_PHF14; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF150; PHD FINGER PROTEIN 14; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 280..341
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 343..460
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 687..741
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 36..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 591..618
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 44..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..229
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 95842 MW; 588267251810A818 CRC64;
GAYSFEKFIM RPLSASQAEV LLSCSFNRND SLLCGFLGSD GTGNGSDEEG SKVSAAGSES
ESNNAASADD GIDDEEVKDL AAEDHFTEDE EKTKPPLSSD NSIKDDPTAT PPKSCRKNKK
TVEAETPPGS NPEATSVSSN TNTEESQSEP KKWNFRRNRP LLDFTTMEDL NEMDDYDSED
DNDWRPNAAK KKSKAAAQKG GDGEEEDGSA SDYDDDNDDD GDDENNSESS DSEKEVKKLK
KQMKSTSGFD EELTNDSMSQ GKGNEDALQD RSQTWSTQHI LICCVCLGDN SEDADEIIQC
DNCGVTVHEG CYGVDGESDS IMSSTSENST EPWFCDACKN GVTPSCELCP NQDGIFKETD
AGRWVHVVCA LYVPGVAFGD IDKLRPVTLT EMNYSKYGAK ECSFCEDARF ARTGVCISCD
AGMCRSYFHV TCAQREGLLS EAAAEEDIAD PFFAYCKQHA DRFDRKWKRK NYLALQSYCK
VSLQERERQL PPEAQARITT RLQQYRTKAE LSRNTRPQAW VPREKLPRPL TSSASAIRKL
MRKAELMGIS TDIFPVDTSD ASASIDGRRK HKQPALSAEF VNYYLERNMR MIQIQDNISE
QKNLKDKLES EQEKLHVEYS KLCESLEDLL NVNGELRSEG QAIWTLLGGI LGQKLNTPPV
LKASKERKPS KKEGGSPGKS SSLPAILYSC GICKKNQDQH LLVLCDTCKL YYHLGCLEPP
LTRMPKKTKN SYWQCSECDQ ASSDDADIAM ETLPDGTKRS RRQIKGPIKF IPQEMSPEPK
KHQVRAQRTR GQKRKRVPIC EDREDKNEEP LPRERRQRQT AMQKKPKTDD TRTECATCKG
PGDNENLVRF FHFFQI
//
