ID H2RRS3_TAKRU Unreviewed; 531 AA.
AC H2RRS3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=CHST15 {ECO:0000313|Ensembl:ENSTRUP00000002839.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000002839.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000002839.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000002839.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|RuleBase:RU361155}.
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DR AlphaFoldDB; H2RRS3; -.
DR STRING; 31033.ENSTRUP00000002839; -.
DR Ensembl; ENSTRUT00000002855.3; ENSTRUP00000002839.3; ENSTRUG00000001214.3.
DR eggNOG; ENOG502QU6N; Eukaryota.
DR GeneTree; ENSGT00390000004719; -.
DR HOGENOM; CLU_017703_2_0_1; -.
DR InParanoid; H2RRS3; -.
DR OMA; LYFKMAN; -.
DR OrthoDB; 3939141at2759; -.
DR TreeFam; TF333516; -.
DR Proteomes; UP000005226; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR15723; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR PANTHER; PTHR15723:SF0; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..476
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 531 AA; 61712 MW; B3442AA6A966DFAF CRC64;
MSLADCSHGC QYNVHRSVAE GCECRPVRTF FDFRYRIMSE NLTGKWPPLF SATNLWSLSK
VKVMSFLMGL TLMFIVMASY LLMWDKEGFL FTASPEQFRP VVILGRPLAT AAPDVSPNGV
LDMKPLVHII DSKLEYTLRT PPELEDVFEA DSHLFSRIPR HFLPSIKSPC WWERFSGDLN
SDPYRKNHFR LSSKSFKTVY EHLKSSFQQH LLPRDGSLFR LRCLPFFYII GQPKCGTTDL
FHRLLLHPDI KFNTMKEPHW WTRKRFGYIR FKDGFRENFS VEDYLDLFDL EAHKIQESLS
GNSGDHHALQ LITGEASAST MWDNQAWSYL HSADEEAEPP FLTQDFIHAI QPDARIIIML
RDPVERLYSD YLYFKVANKS AEDFHLKVLE SIHLFQSCLT MRSLRSCVYN TSLSNAMPVR
LHLGMYVVFI LDWLTVFHQD QILVLRLEDY AANLKTTIKT VFDFLSVGPL SEQAEAALTK
RPMLNRRRAA DRNLGPMLPT TRNLLREFHQ PFNRKLASAL HNKAFFWTSS P
//
