ID H2RUE3_TAKRU Unreviewed; 439 AA.
AC H2RUE3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA polymerase delta subunit 3 {ECO:0000256|ARBA:ARBA00017589};
GN Name=pold3 {ECO:0000313|Ensembl:ENSTRUP00000003760.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000003760.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000003760.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000003760.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2RUE3; -.
DR STRING; 31033.ENSTRUP00000003760; -.
DR Ensembl; ENSTRUT00000003780.3; ENSTRUP00000003760.3; ENSTRUG00000001631.3.
DR GeneTree; ENSGT00940000163239; -.
DR InParanoid; H2RUE3; -.
DR OMA; QMLYDFH; -.
DR Proteomes; UP000005226; Chromosome 22.
DR GO; GO:0043625; C:delta DNA polymerase complex; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1030.20; DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain; 1.
DR InterPro; IPR019038; POLD3.
DR InterPro; IPR041913; POLD3_sf.
DR PANTHER; PTHR17598; DNA POLYMERASE DELTA SUBUNIT 3; 1.
DR PANTHER; PTHR17598:SF13; DNA POLYMERASE DELTA SUBUNIT 3; 1.
DR Pfam; PF09507; CDC27; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT REGION 147..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 48922 MW; F1E908996D5AA3D3 CRC64;
MDDLYLDNID EFVNDHNKIV TYKWLSLTLG VHVNTAKQML YHYLDHKRKE SSAQVHATYL
VSGKFVDNGQ TGHRVSVVRE DQLEDVKSRM SPIVSVHIYS VQKALLKDSG PLYSVDYDAV
KDNLQNCSRY GAVRCSSAVP MSSLELQQAR GARQALPPEP EQKKSSANTD TNVVSKPPSK
PQKGIMGMFA SKAAPKAQES SRDNKSEQEE AARVDPVQSK PARKPNPGAN FFRVQTSKKP
AEEKTSSSPP PAEQNLLPSK PQTKQEAAAV EAPKDAKRES RSKTKRVESD SEEDKTEKKK
RRRIKKPDPD SSDEDVIPDS PPRMETRRLS PSPEKEIPPV TRSQCGNIEG KVRKRRRVLK
SRAFIDDEGC IVTVKDYESE SYSETEDDVQ ATRQAGKDPV PAKPAVSNKQ EDKKGHKKSS
ANANKGAKQA SIMGFFHKK
//
