ID H2SDH0_TAKRU Unreviewed; 765 AA.
AC H2SDH0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=BMP/retinoic acid-inducible neural-specific protein 3-like {ECO:0000313|Ensembl:ENSTRUP00000010451.3};
GN Name=LOC101078868 {ECO:0000313|Ensembl:ENSTRUP00000010451.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000010451.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000010451.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000010451.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BRINP family.
CC {ECO:0000256|ARBA:ARBA00010360}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2SDH0; -.
DR STRING; 31033.ENSTRUP00000069097; -.
DR Ensembl; ENSTRUT00000010509.3; ENSTRUP00000010451.3; ENSTRUG00000004397.3.
DR eggNOG; ENOG502QQZS; Eukaryota.
DR GeneTree; ENSGT00940000156099; -.
DR HOGENOM; CLU_018347_0_0_1; -.
DR TreeFam; TF331600; -.
DR Proteomes; UP000005226; Chromosome 20.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:InterPro.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR InterPro; IPR033237; BRINP.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR15564:SF2; BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3; 1.
DR PANTHER; PTHR15564; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF19052; BRINP; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022810};
KW Growth arrest {ECO:0000256|ARBA:ARBA00022810};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..765
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025493625"
FT DOMAIN 78..264
FT /note="MACPF"
FT /evidence="ECO:0000259|SMART:SM00457"
SQ SEQUENCE 765 AA; 87674 MW; 309ECFCF2099F685 CRC64;
KLLPAACVQC FILSLHCWVC LRSTVAAAAA ATTSLPSDKP GGPLDWLLSD KGPFHHSPEY
IDFVEKNRQG FSTRYKIYRE FGRWKVSNLA VERRDFLESP LPLTPEFIRN IRLLGRRPTT
QMITDNLIRK YGTHFLLSAT LGGEEALTIF VDKRKLSKKA EVSDYAGNSS TVTLEALHQL
AASYFIDRES TLRKLHHIQI ASTAIKVTET RTGPLGCSNY DNLDSVSSVL VQSPENKVQL
QGLQLILPVY LREGFVQAAL SYIACNGEGE FDCKDNDCWC KCDPKFPQCN CPYMDIQAME
ESLQRITETW GVLYKDFEES DEFKAFYTRL PQNYFLNVST IQHLWSLDPG FQWRYEQLEA
SMRLLSRRAQ RVIFKLFSLS KRCSRQPQIH LPRERSQSYW LSHFQSLLYC SENNQLGDFS
EELHSCSCQY EHSPCQLPPP CSVGEGSACA GCAPDNQTRC GSCNPGFALT QGICRPMVAD
STENYLGFET DLQDLELGYL LQRADRRLEV HAIFISNDMR LNSWFDPSWR KRMLLTLKSN
KYKSNMVHML LGLSLQICLT KNSTLEPVLT LYINPFGGSH SESWYIPVNE NNFPDWKATK
LDLPFECYNW TLTLGNKWKT FFETIHIYLR SRIKTQDGLN DSVYYEPLEV TDPARNLGYM
KINSIQVFGY SMHFDPEAIR DLILQLDYPY TQGSQDTAML QLLEIRDRVN RLSPPGQQRL
DLFACLLRHR LKLTASEVVR IHASIQAFSS RLPNSVDYDT TKLCS
//
