ID H2SDU3_TAKRU Unreviewed; 1024 AA.
AC H2SDU3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Next to BRCA1 gene 1 protein-like {ECO:0000313|Ensembl:ENSTRUP00000010574.3};
GN Name=LOC101077097 {ECO:0000313|Ensembl:ENSTRUP00000010574.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000010574.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000010574.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000010574.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2SDU3; -.
DR STRING; 31033.ENSTRUP00000010574; -.
DR Ensembl; ENSTRUT00000010632.3; ENSTRUP00000010574.3; ENSTRUG00000004447.3.
DR eggNOG; KOG4351; Eukaryota.
DR eggNOG; KOG4582; Eukaryota.
DR GeneTree; ENSGT00390000016335; -.
DR InParanoid; H2SDU3; -.
DR OMA; SWELMEA; -.
DR OrthoDB; 5399396at2759; -.
DR TreeFam; TF328428; -.
DR Proteomes; UP000005226; Chromosome 5.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd14947; NBR1_like; 1.
DR CDD; cd06396; PB1_NBR1; 1.
DR CDD; cd14319; UBA_NBR1; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032350; N_BRCA1_central.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR034852; PB1_NBR1.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR20930:SF5; NEXT TO BRCA1 GENE 1 PROTEIN ISOFORM X2; 1.
DR PANTHER; PTHR20930; OVARIAN CARCINOMA ANTIGEN CA125-RELATED; 1.
DR Pfam; PF16158; N_BRCA1_IG; 1.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 4..85
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 88..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..780
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..928
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1024 AA; 110145 MW; 4A337DA45844942C CRC64;
MDFYINLRVN FRGNSKNFLL SGSETKSWES MEAMVKRSFG LCSLQLTYFD EENEEVSINS
QVEYEEALRS AARQGNRLHM NVYETRGQPA RVPTNKTSAT EPKRGFRPPQ HCPALAQVVS
RKVQAAVPEQ GMVIMKEMKG GKDEDKTPPA WFTSYMEKFK DQVVREAVEK ICREFSGQCC
IHKPLGGGSG EGAGGTGRGE AVGGAEAQQV PEVSSSTLPG APSSSTPPCS SCRGQTTGGG
YQCSVCTSCT LCEPCSFSHD PSHNLVRART PLSIPEHGSP APDHSRFYRR GDRSFRKAEK
QRLKAEKRLL KAEVKEIRKQ LRMERRGIQW SSSHREGSSS PVLLQPRATQ HNSPERPKRP
CPLVVPAMMA AFLDENLPDG TRLRPGTKFI KYWKMRNTGT VSWNADTKLK FMWGNLAVGS
GDRWREVSVP FLQPGQVGIV NVALVAPSVE GSYTSHWRLA HAGEQFGPRV WCSIVVDPLA
PAPVMADGIL VSPCVTPQGK NPVTKYGKTC TASREQRLLS VDQEEYYIPS VDLLTAQDLL
SFELLDINIV QELENVPNNT PADRTPCISP LPQDGVLQDK GSPSLGLIQE ETEVINSIMD
MPRPAGSGAD GGGVPAQEEG EDDISGTQFV CETVIRSMTL EEAPDHTPLR GPRPGTVVRP
AAQGGSASSY VKKKTIQAEQ NLGSSPGSSK SAQIHPATLK ASLPSPLKAS LPAPLSVSLT
LGPGPSSAPG PLHATLGAAT LQGHKSTAEG AKSHTETEKT EQEDTAKNEE EKRDGPRSRS
SSTSSEDYII ILPDCFDTSR PLGESMYSSA LSQPGDIPAK TDEEAEPASP DNSTASGAEV
GEAAVLPETG VSGSSSANDM LCTSQTLDDE PLTPEVVAPP TAVVTPRPEC CGEAGGDPGE
AAEGSDLYQN EDASTPEQTQ AGDTGTTEES NPEDPRHPGI TSGLMKGALS VAASAYKALF
TGQGPTQPPV DASTQDTMMA VLVEMGFGDR TLNQRLLNKY NFNLLDVVNE LVQMSDNDWY
STRY
//
