ID   H2SF13_TAKRU            Unreviewed;      1291 AA.
AC   H2SF13;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Hamartin-like {ECO:0000313|Ensembl:ENSTRUP00000010994.3};
GN   Name=LOC101070860 {ECO:0000313|Ensembl:ENSTRUP00000010994.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000010994.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000010994.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000010994.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 31033.ENSTRUP00000010994; -.
DR   Ensembl; ENSTRUT00000011053.3; ENSTRUP00000010994.3; ENSTRUG00000004623.3.
DR   eggNOG; ENOG502QQPT; Eukaryota.
DR   GeneTree; ENSGT00390000014148; -.
DR   InParanoid; H2SF13; -.
DR   OMA; NRMASYS; -.
DR   TreeFam; TF325466; -.
DR   Proteomes; UP000005226; Chromosome 6.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007483; Hamartin.
DR   PANTHER; PTHR15154; HAMARTIN; 1.
DR   PANTHER; PTHR15154:SF2; HAMARTIN; 1.
DR   Pfam; PF04388; Hamartin; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        127..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          296..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          367..451
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          548..600
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1051..1111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1194..1291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          836..877
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          945..979
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        296..315
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..354
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..438
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        548..564
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        572..588
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1054..1108
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1194..1217
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1259..1281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1291 AA;  143547 MW;  ACAB47F42C80CFC8 CRC64;
     MAREQPNVGD LLPLLETSDL HQLDEIRGLI NEHLSTERGS MLLNGLVDYF LETNSMQAMH
     ILSSVREPHD KHLLDKMNEC MTKQSCRLPT LTLLGHVVRK QPSWIHKIAR YPLLLSLLKC
     LKTDTDVVVL ITGVLVLITL LPMIPQAAKQ HLWEYFDIFG RLASWNLKNP GQVSEVYLIH
     LHASVYSLFH RLYGMYPCNF VSYLRSHYSM KENMETFDEV VKPMLEHVRI HPELVTGTKD
     HELDPTRWKK YEIHDIVIEC AKVSLDPKEA SCEEGYSTMP ENVYPQVHLR PQECTSSPYT
     DFQSSYGSSS STPFSTPRQP LPPPLSLPPF SGTLSTYRSP QTSRRQNSSC DLNSSCGAKD
     PLWSPTSLCG MATPPSSRGM SPNLELSHSA SHLPSRFHCT SGGKGTPASS TPATSSPPPT
     LSDDFPIISL PTSTVQSSPP RKERRHGESS RAVLVRQETV KDTDKSAEAG FARDAEAAEN
     VLMTLTELSM FMKKQELELQ LRTEKEKEEA AITEELLKIT EDKRELSALR GFDSPFCHTT
     ETLTGCQAQN KVHSNTQPGG PTRDNHHAAS TPDKSEATAN TSSVGSEGGG GGLSGESRSS
     APALEHSWSY HSGFTPIDHH LHRSSSAPDE DMGKFGMFSP SPCSKPPAPY ESFFYLALPR
     AALLFLGQKT SEAVHKAAME RLSQWEEGVE DGEEEGVVSA SPLEVLDRLV QQGSDTHDKV
     LKRLPLPSKS ADWTHFGGSA PLDELHTLRS QLLLLHNQLL YERYKREQHA VRNRRLLRRI
     INATALEEQN NAMKDQLSLQ STEILSLRES LHVEQQRYRQ LWDDRETMVT RLHSQIRQLQ
     QGRDDYYTKN QELQSKLQEC QKMMDELEAE LQRANNKVCH TGHLLNQMTV KVSNSESTQQ
     QMSFLNKQLL LLGEAHKLSM VESQHTGKDN IKEAQMLKAS FAKEVTALRQ NLLVQEQKLE
     AAQQRVAEME TQLSKKEHLI IEQKKFLEDV KCQAKAEQQA SDSRCQAQRR ITQLLQTELL
     QLYSRVEMEA PAGTASGSPA GGRAVARIHA DSSVTLQDGP SKTFTANEED SRSPPDSPQG
     NGSTLSPGQP KANNSSKTTT NSINGSQDLA PPLLVEPSLS CSYSNQLAPR PLSDTPLTVG
     SYPSAKSFLG MKARELFRNK SESQCDEEQP RPRLAGLAHD LKTELCVEPP CPAYSAPSGP
     APCPIPTQIP AAAPAPTAPL TVPTKQRPLE PKQRASSQES PRRKAGAGPG GGRGHAGPVR
     PQQQQQQQQQ QQQQPQQLKI MDYNETHHEH S
//