ID H2SHR5_TAKRU Unreviewed; 423 AA.
AC H2SHR5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Zinc finger CCCH domain-containing protein 15 {ECO:0000256|ARBA:ARBA00015073};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000011947.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000011947.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000011947.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ZC3H15/TMA46 family.
CC {ECO:0000256|ARBA:ARBA00010043}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2SHR5; -.
DR STRING; 31033.ENSTRUP00000011947; -.
DR Ensembl; ENSTRUT00000012007.3; ENSTRUP00000011947.3; ENSTRUG00000004988.3.
DR GeneTree; ENSGT00390000015818; -.
DR HOGENOM; CLU_042870_3_0_1; -.
DR InParanoid; H2SHR5; -.
DR OMA; AMIFKPV; -.
DR Proteomes; UP000005226; Chromosome 4.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.20.400.10; -; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR032378; ZC3H15/TMA46_C.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR12681:SF0; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15; 1.
DR PANTHER; PTHR12681; ZINC FINGER-CONTAINING PROTEIN P48ZNF; 1.
DR Pfam; PF16543; DFRP_C; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 99..126
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 174..212
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 99..126
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 174..212
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 218..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 11..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..318
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..423
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 48114 MW; 616A76AE4563FCC4 CRC64;
MPPKKPAPAS GNKKTQEKKK EKIIEDKTFG LKNKKGAKQQ KFIKNVTQQV KYGQQSGRQV
AQADQEKGSK KTDKKKELDQ LNELFKPVVA AQKVSKGVDP KSVLCAFFKQ GQCTKGDKCK
FSHDLSVERK CEKRSLYVDE RDEELEKDTM DNWDEKKLEE VVNKKHGEAE KKKPKTQIVC
KHFLDAIENS KYGWFWVCPG GADTCMYRHA LPAGFVLRKD KKKEEKEEEI SLEELIENER
AALGHNVTRI TLETFLAWKK RKKQEKVDKA REDLEKKKAD FKAGKSLTVS GREVFEFRPE
LVDDDDAEAD DTEYDKNKED EEEVNVSVEV QDIDLSRFVP KEVDNTGITM ATMDRFTSRN
KTQPTEIDEE QLNGACGGAE VNGLSGAEGG SEEDEEVPVD ENLFTGEDLE ELDEELSTMA
LED
//
