ID H2SWW5_TAKRU Unreviewed; 563 AA.
AC H2SWW5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Gamma-adducin-like {ECO:0000313|Ensembl:ENSTRUP00000016903.3};
GN Name=LOC101064298 {ECO:0000313|Ensembl:ENSTRUP00000016903.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000016903.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000016903.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000016903.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}.
CC -!- SIMILARITY: Belongs to the aldolase class II family. Adducin subfamily.
CC {ECO:0000256|ARBA:ARBA00006274}.
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DR AlphaFoldDB; H2SWW5; -.
DR Ensembl; ENSTRUT00000016976.3; ENSTRUP00000016903.3; ENSTRUG00000022794.2.
DR GeneTree; ENSGT00940000155257; -.
DR Proteomes; UP000005226; Chromosome 17.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR001303; Aldolase_II/adducin_N.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR PANTHER; PTHR10672; ADDUCIN; 1.
DR PANTHER; PTHR10672:SF5; GAMMA-ADDUCIN; 1.
DR Pfam; PF00596; Aldolase_II; 1.
DR SMART; SM01007; Aldolase_II; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 143..325
FT /note="Class II aldolase/adducin N-terminal"
FT /evidence="ECO:0000259|SMART:SM01007"
FT REGION 530..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 63357 MW; 749F5B2DCC5C4897 CRC64;
QMTTELLKVE TGVVTTPPLP SGGTKERYFD RIDVNDPEYI RSRNMSPDLR QDFNVLEQKK
RVTQILQSPA FKEELESLIQ EQQRKGNNPT GLLALRQIAD TLVASSVAGF SASPLSLGMV
TPINDMYGAE YATMVKGEKV TRCKLASLYR LVDLFGWAHF GNAYVTCRVS KEQDHILILP
RGLSFAEASA SNLVKLNIIG EVIEQGSTNL RTDPTGFSPH AAIYSIRPDI RCVIHVHTPV
TAAVSSMKCG ILPISQEAMI LGDVAYYNYQ GSLDDQEECR ELQKALGPTA KVLVLRNHGM
VALGETIEEA FHFVYNVQYA CEIQVNAVSC AGSVDNLVML DPEKYKSLVY DVAMDSSFAM
CSQYKWKAGE LEFESLMRML DNLGYRTGHT YRQPIVREKP RHKSDVEIPA TVTAFMFAED
MDGAPTRLPL KFLQQRQQRE KTRWLNSPNS YTKVNVDGGE DRYNSRTTTW MKAEETGTPI
RIEDPNQFVP LNTDPIEVLQ KRNKPYVPTE EEQMAPLPPN PFSELLEKDT EERPKNVERR
QLGLSGTPAH THTHTHTHTH TQT
//
