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Database: UniProt
Entry: H2T3Y0_TAKRU
LinkDB: H2T3Y0_TAKRU
Original site: H2T3Y0_TAKRU 
ID   H2T3Y0_TAKRU            Unreviewed;      1214 AA.
AC   H2T3Y0;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   28-MAR-2018, entry version 33.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000019368};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000019368, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000019368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000019368}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   Ensembl; ENSTRUT00000019446; ENSTRUP00000019368; ENSTRUG00000007795.
DR   eggNOG; KOG3614; Eukaryota.
DR   eggNOG; ENOG410XR5B; LUCA.
DR   GeneTree; ENSGT00760000119127; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR032415; TRPM_tetra.
DR   InterPro; IPR037162; TRPM_tetra_sf.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    784    803       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    851    869       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    881    899       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    920    940       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    996   1021       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      790   1030       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1125   1180       TRPM_tetra. {ECO:0000259|Pfam:PF16519}.
SQ   SEQUENCE   1214 AA;  138611 MW;  8EA25FB6A7406C71 CRC64;
     HRCSCGQLIA QHHFLPVGNK EEGAPLVDVD VRTTEKWSIL KHTQPSPTDT YGVLEFQGGG
     QVNKATYIRV SYDSKPDNLL HLMVKEWQLE LPTLLISVHG GLQNFDLPPK LKQVFGKGLI
     KAAVTTGAWI FTGGVNTGVI SHVGDALKDH SSKSRGKVCA IGIAPWGIIE NKEDLIGRDV
     TRPYQMMSNP FSKLSALNSS HSHFILSDNG TTGKYGAEVR LRRQLEKHIA LQKINTRLGQ
     GVPVVCLILE GGPNVISIML ESLREEPPVP VVICDGSGRA SDIISFAHRY CEEDGMLSDN
     IKDQLLVTIQ KTFNYSRLQA QQIVLMVMEC MKKKSLITVF RMGLEGQQDI EMSILTALLK
     GTNASAADQL SLALAWNRVD IARSQIFVFG LHAPVNSLEQ AMMDALVLDR VDFVKLLIEN
     GVNMNHFLTI PRLEELYNTK LGPVNTLHIV VRDVKKDDAF VWKDATGNLP PDYQITLIDI
     GLVLEVLMGG AYRCKYTRKS FRTLYNHLYG LKRPKALKLL GMEDDEPRSK GRGKKSKKKE
     EELDVDVDDP EVSRFQYPFH ELMIWAVLTK RQTMALFLWQ HGEEAMAKAL VACKLYKAMA
     HESSQSELVD DIFQDLENNS REFGQLAYEL LDQSYKRDEQ VAMKLLTYEL KNWSNSTCLK
     LAVAAKHRDF IAHTCSQMLL TDMWMGCLRM GKSNSLKVIL GIIFPPAILL LDFRLGDEAS
     NRPNRNNEDR GTKDEDSKSS KDAASNLDAT SKKGDDEEEQ NKIKRRTPVV RTIFEFYNAP
     FTKFWFNTIS YLVYLMLYNY IILVKMERWP SLQEWTVIAY IITLGLEKRS QILMSEPGKL
     KQKINVWLED YWNITDLVAI SVFLLGLLLR LQNEPSMGYG RVIYCVDIIF WYIRVLDIFG
     VNKYLGPYVM MIGKMMIDML YFVVIMLVVL MSFGVARQAI LHPDEEPTWR LARNIFYMPY
     WMIYGEVFAD SIDPPCGDNL YDEDGKKLPP CIPGAWLTPA IMACYLLVAN ILLVNLLIAV
     FNNTFFEVKS ISNQVWKFQR YQLIMTFHDR PILPPPLIII SHIYILLRRL FCPCRQRPDG
     ERDHRERGLQ LVLNLDELKS LHEFEEQCVE EYFREKDDEK QSSNNERIRV TSERVENMFM
     RLEEVNEREH SMKASLQTVD LRLAQLEEFS GRMMHALEKL AGVERDELFA TRSRGSSVCE
     LSLLRHGSVN SGDG
//
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