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Database: UniProt
Entry: H2T438_TAKRU
LinkDB: H2T438_TAKRU
Original site: H2T438_TAKRU 
ID   H2T438_TAKRU            Unreviewed;      1757 AA.
AC   H2T438;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   20-JUN-2018, entry version 39.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000019426};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000019426, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000019426}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A.,
RA   Hosoya S., Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu
RT   facilitates insights into distinct features of genome evolution in
RT   teleosts and mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000019426}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   Ensembl; ENSTRUT00000019504; ENSTRUP00000019426; ENSTRUG00000007814.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   Gene3D; 1.20.120.350; -; 4.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR024583; Na_trans_cytopl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   Pfam; PF11933; Na_trans_cytopl; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    121    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    159    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    230    247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    253    273       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    393    420       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    761    779       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    791    814       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    871    899       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    929    947       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    959    984       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1207   1225       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1246   1264       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1323   1349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1446   1469       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1528   1546       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1558   1576       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1583   1608       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1645   1673       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      131    426       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      558    684       Na_trans_cytopl. {ECO:0000259|Pfam:
FT                                PF11933}.
FT   DOMAIN      761    989       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      998   1201       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN     1205   1478       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1527   1757       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       21     41       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1757 AA;  198819 MW;  AC74CA3D6E3D8C22 CRC64;
     MAGCVFPMGP ESFQRFTPDS LAAIEQRIIQ EEARLKKQYK EDLGDVELPQ ARPDLEAGKQ
     LPRIFADIPS HLVGVPLEDI DPYYFRDKRT FIVLNKGKAI FRFSATSALY FFSPFHPVRR
     IAIKILVHSY TLFSLFIMCT ILTNCCFMAM SEPANWAKYL EYTFTGIYTF ESLIKILARG
     FCVGPFTFLR DPWNWLDFSV IVMAYVTEFV DLGNVSALRT FRVLRALKTI SVIPGLKTIV
     GALIQSVKKL ADVMILTVFC LSVFALIGLQ LFMGNLRQKC VRSTAHCVND SLPANASFFC
     NNKTWTSMKD FINEEENFYK AEGAKDALIC GNGSDAGKCP DGFECLKTGR NPNYGYTSFD
     TFGWAFLSLF RLMTQDCWEN LYHQTLRSAG KTYMVFFVVV IFLGSFYLIN LILAVVAMAY
     EEQNQATIVE ECQKEREFQV AMERLKKDQQ VDQQESKFTF ASSVLSKAAA QKALDSDSVM
     SPELSPFALP LDHQEGRRQS QVLVGVAEAE ANLSEEKLLQ VDVTDGGKVR EEESGPFLLA
     APLGEPVHPL LARSFSAKTR RSSQVSSIFN FRLRSRGSEG EMADDEYSVP EDVIEGVGGG
     TYSGGTFSGI LSHPWPKRRP STYSTTSRSS QVFYPTLNIN GKLFVTMDQN GVSPPPLQGQ
     LPACTMEKVN LPEGTHKAPT STTELSTMLL PRPSSLQGSV SRGRALSAAS YLTDAMEELE
     EAHKRCHPCW YAFAHRFLVW ECCPCWLKVK QLVKVMVMDP FLDLAITICI VLNTLFMAME
     HYPMTEEFNG MLSIGNLVFS GIFTAEMVLK IIALDPYYYF QTGWNIFDSI IVCLSLMELG
     LSNVEGLSVL RSFRLLRVFK LARSWPTLNT LIKIIGNSMG ALGNLTLVLA IIVFIFAVVG
     MQLFGKNYQD CVCKISKDCT LPRWHMKDFF HSFLIVFRVL CGEWIESMWD CMEVAGQPLC
     ILVFMLVMVI GNLVLLNLFL ALLLSSFSSD NLSAPDEDGE MNNLQIAIHR ITRGLAWCRK
     QVVDFFNGNL KRRRQKQKEA KAMMKLKRLS SIHMEVNGAV IGAETSEPPN DYVVVPGRQM
     EKYVPPEDDS YMTNPNLTIS VPIAPGESDV EFPEDEDEDG EEEEEESEAS QEEEESLSEG
     STVDLRKPGE EEDEYSEMAE EAMDPENCFP DVCVARFQCC DLNTTAGLGQ MWWRTRKTCY
     QIVEHSWFES FIIFMILLSS GALAFEDIYI EQRKVVKVIL EYADKIFTYI FILEMLLKWL
     AYGFKKYFTN YWCWLDFLIV DVSLISLVAN TLGYSDFAAI KSLRTLRALR PLRALSRFEG
     MRVVVNALIG AIPSIMNVLL VCLIFWLIFS IMGVNLFAGK FGRCVNRTGH IYEAAFINNK
     SECEALNDTS LFYWTKVKVN FDNVGAGYLA LLQVATFKGW TDIMFAAVDS RAVEEQPIKE
     VNLYMYLYFV IFIIFGSFFT LNLFIGVIID NFNQQKRKLG GQDIFMTEEQ KKYYNAMKKL
     GSKKPQKPIP RPLNSLQGFF FDLTGKQAFD IIIMVLIILN MITMMVETDE QSPQMEYILN
     NINLAFIVIF TTECLIKIVA LRYYFFTVGW NIFDFVVVIL SIVGIVLADI IEKYFVSPTL
     FRVIRLARIG RILRLIRGAK GIRTLLFALM MSLPALFNIG LLLFLVMFIY AIFGMANFAY
     VKRQAGIDDM FNFETFGNSM ICLFQITTSA GWDTLLSPIL NNSPEECNPN IPHTGTTVRG
     NCGNPSVGIT FFVTYII
//
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