ID H2T6D1_TAKRU Unreviewed; 605 AA.
AC H2T6D1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Bromodomain containing 7 {ECO:0000313|Ensembl:ENSTRUP00000020220.3};
GN Name=brd7 {ECO:0000313|Ensembl:ENSTRUP00000020220.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000020220.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000020220.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000020220.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2T6D1; -.
DR Ensembl; ENSTRUT00000020304.3; ENSTRUP00000020220.3; ENSTRUG00000008098.3.
DR GeneTree; ENSGT00950000183170; -.
DR Proteomes; UP000005226; Chromosome 13.
DR CDD; cd05513; Bromo_brd7_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR021900; DUF3512.
DR PANTHER; PTHR22881; BROMODOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22881:SF12; BROMODOMAIN-CONTAINING PROTEIN 7; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12024; DUF3512; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 131..201
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 605 AA; 67877 MW; 937C18F6CA397C6E CRC64;
MGKKHKKHKS EKHGYEDYGE RPLKLVLKVS GNEVTTGSSS RDTFYDEQSA ELDKPKEKKK
KKKKDKERNL GSPVDDRGKK KMTKKRKGQD ADGEDDGEQC RTPIRSELDK LEKKEQTPLQ
EALNQLIRQL QRKDPSAFFS FPVTDLVAPG YSSIIKRPMD FSTMKDKVKK ECYQCLDELK
VDFKIMCENA MIYNKPDTIY HKAARKLLHS GMKILSQERL ESLKQSIMFM SGLDNSTTQP
TKSEEQGGSG VDQKHERSSI TDSSESSQTP STPRQEKDSK DEVAKAEKEL EEIHKVIEES
GGKLSNRLLQ CDLEFARRRS DGSTTLAIVN PADPAVGDVG YCPVKLGMMS SRLQSGVNTL
QGFREDKRNQ ISLVSYINYG PYTSYAPTYD SNFGNVSKEE SDLIYSAFGD KSSLQGSDSL
PEFLAKSDEY VYKLADNLLD ALTNGEHSKT LQETEGRVHA GRRMNECIVF HMCNQGRGGQ
CEVTGGNINP PVSYFSVTDA LRVQQKLDET TRLLHDLQEA QKERLSTKQP PNMICLLAPT
EKELELAEKV TENLAGMTSQ VAPCDVSSVY GIRRAMGIAV PLETESFIDL TTGEHLTIEI
FVYAF
//
