ID   H2T8I3_TAKRU            Unreviewed;      1279 AA.
AC   H2T8I3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Transducin beta like 2 {ECO:0000313|Ensembl:ENSTRUP00000020973.3};
GN   Name=tbl2 {ECO:0000313|Ensembl:ENSTRUP00000020973.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000020973.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000020973.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000020973.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MYBBP1A family.
CC       {ECO:0000256|ARBA:ARBA00006809}.
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DR   AlphaFoldDB; H2T8I3; -.
DR   STRING; 31033.ENSTRUP00000020973; -.
DR   Ensembl; ENSTRUT00000021060.3; ENSTRUP00000020973.3; ENSTRUG00000008378.3.
DR   eggNOG; KOG1926; Eukaryota.
DR   GeneTree; ENSGT00390000017457; -.
DR   InParanoid; H2T8I3; -.
DR   OrthoDB; 2911826at2759; -.
DR   TreeFam; TF317401; -.
DR   Proteomes; UP000005226; Chromosome 15.
DR   GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR007015; DNA_pol_V/MYBBP1A.
DR   PANTHER; PTHR13213:SF2; MYB-BINDING PROTEIN 1A; 1.
DR   PANTHER; PTHR13213; MYB-BINDING PROTEIN 1A FAMILY MEMBER; 1.
DR   Pfam; PF04931; DNA_pol_phi; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   REGION          712..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1165..1279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          629..658
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        713..733
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        734..779
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1165..1185
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1279 AA;  144313 MW;  610C19D07009D3C2 CRC64;
     MSVKMVEMST KTVGPVRSAG ILQQNRVFLD FFWDLAKPDQ EVRLKAIEDL IQYLKANNKA
     DELEYTFKRL VDGLAHSREA ARPGFSLALG QVLNAFEDVT LQSTLNRIKQ KHNLQTVKKN
     LIRNALFGNF FGVLALQQSG RLSKEPQVVL GCVQLLQSLS QHRQHLRDLP NKTMMDILNE
     ISEEVFEEVL LSALQADLAA AFRTPEQLQL LLVALQRFPQ TLKPQKLKKL LGSSTIINTD
     NIPKLTQMLN TAAQSSKKDH VLPAVALDLL KLSLKEGSFQ LFWNHTIVKG MLKEQQGPAH
     YLCFRLLGSS LPYLSIAQLK EVLRGEVMMH YGEHVVSAQK PDRFKLAPEM EVYVSDFLQG
     CQDPDKQLAV MVSFSSLTNQ GYPVVPSVWR VVQHLQPVAL QQYVAWLKKM FLQPQQDELL
     DISTHKQKGN QEGKEQKENS VFRLRKWLVA RLSSIIDNYQ VKRQEDLIMD VARFVFFHAF
     FTTKKPSADI PETNNKLSVP LDDGTRGVLI NSFFGLLLSM HHMPLAEEVG EGASVNSKRV
     LGVTADGTMW IYHLVQYAQV LLKQPKHVEC SQPFSPEQRQ AWDSMLESVA NLKKKAKKAS
     TAENSAFQQL FLLVGMHLFK APEELLDIMK DLQSCVDKAQ EKKAKKKKKQ TAAQQEEEPE
     WVEVMVDILL SLLSQPSRHI RQVCKTVFSS ICPNVTPAAL NAILDVLDPE KDDEENSAVV
     ITDDTKSLKK EDEDDEEMEV DDSDASDDDD DDDDDDNEEE EEDDDDAMED DEEEELEEGV
     VDQNFRLELM KVLQQQNALA EDASSDEDLD DEAMMELDKN LAAVFLEQKK KTQAKKDEKT
     KIMKEKTLVR DFKIKVLDFV EVLVGRQAGS PLVLSLVEPL LHIIERGMSS DSQQQEQDFL
     RRAADIFRNQ LCRSKVYCKT VGDRQGALHD MLEKLMSKTQ KLADSSVSLY YFSASLYVVK
     VLRGAPPAGT QQENSTTAAD LRFTGSLDMD RVTAIFREAL NSFMSKRKSP LTTQMFTDLF
     NRFPVLGVNL LDAAVQHIKS GVRVHQQGQA CVLVLRAMQS REIQQLLGGP AWTDLCTKVT
     AQLAASLQQV DQLDNKLVKE KVVKTLELCQ FLVKQVHQQK LSVDLEPLKK ALEALPNAIT
     FNKTGKLEDT YWAVVKHFGV TKPKVEKMKP DKEAEPQPAQ KKKKGFLPET KKRQKRMKPV
     LEPAGEKPTS VDNAGAEGEH AKKKKDKKTK RKPATGEAND AQPGSAKKRK KQSSAQRSKT
     PSDSNPAKKK KPKQKKEKA
//