ID H2T8K3_TAKRU Unreviewed; 691 AA.
AC H2T8K3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Spermatid perinuclear RNA-binding protein-like {ECO:0000313|Ensembl:ENSTRUP00000020993.3};
GN Name=LOC101078718 {ECO:0000313|Ensembl:ENSTRUP00000020993.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000020993.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000020993.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000020993.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2T8K3; -.
DR Ensembl; ENSTRUT00000021080.3; ENSTRUP00000020993.3; ENSTRUG00000008384.3.
DR eggNOG; KOG3792; Eukaryota.
DR GeneTree; ENSGT00940000154687; -.
DR InParanoid; H2T8K3; -.
DR OMA; CNRLPEW; -.
DR TreeFam; TF320194; -.
DR Proteomes; UP000005226; Chromosome 21.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1410.40; -; 2.
DR Gene3D; 3.30.160.20; -; 2.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR PANTHER; PTHR45762:SF1; SPERMATID PERINUCLEAR RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 5..384
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 405..471
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 523..589
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 49..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 166..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..217
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 691 AA; 76297 MW; 20E34406C94902D8 CRC64;
MRLLRSFAND DRHVMAKHAS IYPVPEELEA VQTLVSTVEG ALKKVSDWMD GLNQPSGKTS
DEAGENMVEK DPEEAKSDSV PLLCGVTRVG LVAKGLLIKG DMDLELVLMC KEKPTKLLLY
TISTNLPLQI QTMTEDKYEV CSCVPEAAIR VCRTKDPQLT LKITLSSLTM REEHGSRQEE
EGDQDNMKEQ QQQEQQQQEE QQEEEEQQQE EEEQQEDALD GQKCRAALAS LRHTKWFQAR
VTDLKSCIIV MRIFRDMCNR RPEWQPVKGW PLELICEKAI ATCNRPLGPG EALRRVLECI
ASGILLPGGP GVHDPCERDP TDVLSDLSPQ QADTITDSAQ HALRLLAFGQ LYKVLNMDPL
PASKPSPRLL EGGCQKRFRE DVGSDDRDFI KRMKVLDWRM MDPNHPMNAL MRLNQIHPGL
QYRLLSQSGP VHAPVFTMSV DIQGTTYQAT GNSKRTAKLQ VALKALQALG FVLSGDGDVD
SLSSDEKSDG EGKMDRMSSS SSSIASSTDT QESRAPGPIL TAGGKNPVME LNEKRRGLKY
ELISESGSSY DKRFIIEVEV DKQVFRGMGP NKKVAKASAA LAALNSLFSG SKTATIKKKR
PNPTPKRPLT SVLTLPALAA SPVRMPIIPR APYISTPPAH GYIPPGFGAP YGYSPAGALP
PYGFPSRMTS VVVPVIRVPT AYPPVTHLYP Y
//
