ID H2TCJ9_TAKRU Unreviewed; 2751 AA.
AC H2TCJ9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 10-FEB-2021, entry version 45.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000022391};
GN Name=cenpf {ECO:0000313|Ensembl:ENSTRUP00000022391};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000022391, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000022391, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000022391}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
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DR RefSeq; XP_011607920.1; XM_011609618.1.
DR RefSeq; XP_011607921.1; XM_011609619.1.
DR STRING; 31033.ENSTRUP00000022391; -.
DR Ensembl; ENSTRUT00000022484; ENSTRUP00000022391; ENSTRUG00000008905.
DR GeneID; 101075530; -.
DR KEGG; tru:101075530; -.
DR CTD; 1063; -.
DR eggNOG; ENOG502QVMD; Eukaryota.
DR GeneTree; ENSGT00730000111187; -.
DR HOGENOM; CLU_000551_0_0_1; -.
DR InParanoid; H2TCJ9; -.
DR TreeFam; TF101133; -.
DR Proteomes; UP000005226; Chromosome 13.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 1.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 1..300
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1775..1917
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2013..2152
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2647..2687
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 50..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1631..1652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2121..2144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2348..2371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2591..2630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2714..2751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 167..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 273..293
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 308..328
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 336..356
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 361..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 432..501
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 509..529
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 555..603
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 706..733
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 773..800
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 812..832
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 843..863
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 889..951
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 997..1017
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1081..1101
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1127..1203
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1221..1314
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1353..1373
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1381..1401
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1423..1443
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1561..1581
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1660..1687
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1695..1722
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1779..1876
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1898..1946
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1989..2086
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2181..2215
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2223..2278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2296..2334
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2426..2446
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2455..2527
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2542..2562
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 50..65
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..159
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2614..2630
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2716..2731
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2732..2751
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2751 AA; 316795 MW; 6B55ED8C0EDBC4D1 CRC64;
MSWAVEEWKD GLPVKALQKI QEMEVHLDKL KKERTQKQFK LDSLEAALQK QKQKADIERT
ESSALKRENQ SLVESCDSLE KSRQKLAHDL GIKEQQVSYL EGQLNSCRKT TECLEQELKK
YKNELERSQS AGSSLSSSSE LQPYTTPQKS IPTPLPVTAN RHQDNRLEGL EEEYNLEVKE
RKKLETELKV LQVKLENQSS ATVSHKDFVA RQAGSSIFPW QQDQAHSWQI QDAVETPVKR
RGTSLWDVHE ETPIKPSQRM SSLQSPARSC QQMEQLKTLN QELCGRVSEL ERILSTQQKD
ICNQASKLQE LQTLLVQARK ELTERDRDLT KTSHDLSQAE SKCSMVEEKL KQMAEEMSCQ
RHNAESCRRV LEQKLKDQER ASQEELAQLQ GSHQTLEQQL DQTRTKLTQE IQQSKKDLNF
LQADMEKMCF QKNQMMKELK EQKQKLLRSE QNLQACQNKE HDVQKKIEEL QKEKNSLTVQ
LDQSSRCLTQ LEEEKKKTEQ LLKCTHGLLD DLKAKSEGQT EELNRIRSKL EHQTQMSASE
LLNMNKALCD AETKTERAQN ELDKHKQKAE KLANRLTLLG NENQEQKSNI TAGQKECDHL
KKEIQALLDW KKEKETLINY TETIQKELNE KIVTLEKSLI SANEVTDQLK LQNVSIEEDK
ASLSAHLHAL KGELLSKCTK LEERDHQFMT LQAEFSETGQ KHAKDFENIA VQVKQLEAQV
KELEVQLQEE VTRAGQAKRI NLELRGEHQA ACDLVQSKNR LLELGQAEII QLRESLSQAI
AQQEEQGARL ADEREALLTQ CEETVSLKVE GIEQLKWQLE AAQQELLLFK DQVTSMDLCK
EVKGQLEAEL QKQITKLLDQ EEEHRKIYEI QSEEIRQLKD VLKELHCCLE DEQKLLRDSE
AQISSLKKQN TKLENAAQET ETLREAQVGE INSLLEQISF LQQELTVTQD AVKGLQLLND
ELDMVNHSHA ELKKCMEDLG RSHSSTLEIK SNLENNLTEK NSLIITLKVE VQKLKEQMCQ
DAESHTQQIN NCLNKQRWLQ EQLDEAKKIE TATKAESKSQ REEIKTMKTT LSAASQCLEE
RDDLIESLKE KLCKAEEEQA KTSDLLREKV VSMNKVKVQM EMLQMDLEDN EMAMNTFNSQ
VEELKATRDT LNSQLGQKQL QISDMEAKLE EYKAQVSVLE TRLEEVQSQN SLLEMQYITA
KEELTERSCE VTCLEEGAVK ISQLNETVAA LQLKLGHITE ENNKLEKLRQ IMEGKDSDIN
QLLQDKHILE TKVKQLIDEK ERVDANIIQV NAQKNHLEAS LNTLTEENQE LQSCMKWITE
EKDKIDEVVL EKLEAKSSLR QVTEEKTQLA ATLSLLDQDK IQLETEVKEL AIEESNTVAK
LNQVVDEKLQ LSCQCDQLTK ENIHLQSSLH KLAEDKLLMQ GSIQKFEKEM ISLEDKNKCI
QSALLSSQQM VEILKEQLET QDKGAEERRE RSKQFEVQQV ALHQQLLVLQ MELAAMRQLY
DSLLEQVSQQ NGFIQQLSDL QKTLKSEDNV SGRESKKTET VAGQMNADMT EDTSVESLPE
MEQLSCEVAE LKEHSHQSEE DFCETQLVHK EHTGDKMMQE CLDVAKNVCV PDPLETVEEQ
HLQQTEALNT SLSGLPSSSL PESSQSEISE KASPQVRDYL NNYKNIIISQ ENQLQQLYAE
FDLLKSDLML RMELTSELQA EVQNWEKKFQ RAEEEKLVAL HKLNITLENH KVVTDQLTRL
SEEKETLALQ LQTSKCQLTD VIEMLGGLQM TKGGWDDKFL QQESELKRVR SEKSNLEQHI
LGMESDLENL QEERTKLKTE VETQRKVCSG MEQEIDTLRT ELTQLRAELV SCSEERDDLN
QSLGQWRNKV DTLERTNCDT RNLISILEDD IRTGRREHKV LKTSIEELAS EKQQLLEQIK
TLELAISEQN GERQELIGQL DKITEDHLSA HQNTETMVGK IQALEGEVYH LSQSLEASLV
EKGEIASRLN STQDEVQQMR TDIEKLYIRI ESDERKKKKM RELLKAAQRK SDSLQDHIDA
LVREHADIES SLEEAVLQAE TSKEELEEER RKVEEEKMVL SNKLSEFSIA LQHLRSEKKH
VELELKNREI EDLKAAKEDM ERGLERAEAG KRQKEERQKH RVEQLEKEVK EDAERITRQL
DDLRDQLQAC HQRELYLEGK SIETEADKER LKSLLADLEM DKNHLQTLLE ELQTGRDSLC
SQTAERKREI HNLKTDINTL KEERNDLKIK IKAKEEEREN LQCSLVSLQG EKERIEQESQ
VLVFDKEKLQ SYLCLIEKEK QEMQQILSSL KEEKDSIEEE RNDLAAEREE LLSLLFVVEK
EKNDLSSITS SLEQENQNVE EKKEKLTGDQ GRLQSTVASV QEQLEMCKPS VSKRHEQVSD
RTNVVTRLSK ERDSALSKMS RCMKTCKQLE QEKEVMLNSI DEVKNNAAQM EISQLQHAEK
RNMDMEDLKM VLQQKKNEVE EQTKEVDELK AALIGREEEL MERNGELQEL KNELTKLKNI
LEVKSMEADE SMDKYCNLMV QVHKLEETNA ALTTRLEQLS ASQNANNGKV VSDCVQHQRF
TRKLAIKPRE ENLAVGNENT APSTPLRIPQ GSKRGHSDLS EKARHLPDLD LTKKIKTNLV
NGAQEQTDQE DEDFRPEGLP ELVQKGFADI PVGEASPFII RRTTVKHYSS QLAGRHSVPT
PVCKVLGPVS IHNPSKDSHM CLSPKQHPQS LGRTPEQKEK QTHQGDNCHV Q
//
