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Database: UniProt
Entry: H2TCJ9_TAKRU
LinkDB: H2TCJ9_TAKRU
Original site: H2TCJ9_TAKRU 
ID   H2TCJ9_TAKRU            Unreviewed;      2751 AA.
AC   H2TCJ9;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   10-FEB-2021, entry version 45.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000022391};
GN   Name=cenpf {ECO:0000313|Ensembl:ENSTRUP00000022391};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000022391, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000022391, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000022391}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   RefSeq; XP_011607920.1; XM_011609618.1.
DR   RefSeq; XP_011607921.1; XM_011609619.1.
DR   STRING; 31033.ENSTRUP00000022391; -.
DR   Ensembl; ENSTRUT00000022484; ENSTRUP00000022391; ENSTRUG00000008905.
DR   GeneID; 101075530; -.
DR   KEGG; tru:101075530; -.
DR   CTD; 1063; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   GeneTree; ENSGT00730000111187; -.
DR   HOGENOM; CLU_000551_0_0_1; -.
DR   InParanoid; H2TCJ9; -.
DR   TreeFam; TF101133; -.
DR   Proteomes; UP000005226; Chromosome 13.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 1.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   DOMAIN          1..300
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1775..1917
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2013..2152
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2647..2687
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          50..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          125..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1631..1652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2121..2144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2348..2371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2591..2630
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2714..2751
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          167..201
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          273..293
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          308..328
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          336..356
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          361..424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          432..501
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          509..529
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          555..603
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          706..733
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          773..800
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          812..832
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          843..863
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          889..951
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          997..1017
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1081..1101
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1127..1203
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1221..1314
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1353..1373
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1381..1401
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1423..1443
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1561..1581
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1660..1687
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1695..1722
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1779..1876
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1898..1946
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1989..2086
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2181..2215
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2223..2278
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2296..2334
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2426..2446
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2455..2527
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2542..2562
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        50..65
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..159
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2614..2630
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2716..2731
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2732..2751
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2751 AA;  316795 MW;  6B55ED8C0EDBC4D1 CRC64;
     MSWAVEEWKD GLPVKALQKI QEMEVHLDKL KKERTQKQFK LDSLEAALQK QKQKADIERT
     ESSALKRENQ SLVESCDSLE KSRQKLAHDL GIKEQQVSYL EGQLNSCRKT TECLEQELKK
     YKNELERSQS AGSSLSSSSE LQPYTTPQKS IPTPLPVTAN RHQDNRLEGL EEEYNLEVKE
     RKKLETELKV LQVKLENQSS ATVSHKDFVA RQAGSSIFPW QQDQAHSWQI QDAVETPVKR
     RGTSLWDVHE ETPIKPSQRM SSLQSPARSC QQMEQLKTLN QELCGRVSEL ERILSTQQKD
     ICNQASKLQE LQTLLVQARK ELTERDRDLT KTSHDLSQAE SKCSMVEEKL KQMAEEMSCQ
     RHNAESCRRV LEQKLKDQER ASQEELAQLQ GSHQTLEQQL DQTRTKLTQE IQQSKKDLNF
     LQADMEKMCF QKNQMMKELK EQKQKLLRSE QNLQACQNKE HDVQKKIEEL QKEKNSLTVQ
     LDQSSRCLTQ LEEEKKKTEQ LLKCTHGLLD DLKAKSEGQT EELNRIRSKL EHQTQMSASE
     LLNMNKALCD AETKTERAQN ELDKHKQKAE KLANRLTLLG NENQEQKSNI TAGQKECDHL
     KKEIQALLDW KKEKETLINY TETIQKELNE KIVTLEKSLI SANEVTDQLK LQNVSIEEDK
     ASLSAHLHAL KGELLSKCTK LEERDHQFMT LQAEFSETGQ KHAKDFENIA VQVKQLEAQV
     KELEVQLQEE VTRAGQAKRI NLELRGEHQA ACDLVQSKNR LLELGQAEII QLRESLSQAI
     AQQEEQGARL ADEREALLTQ CEETVSLKVE GIEQLKWQLE AAQQELLLFK DQVTSMDLCK
     EVKGQLEAEL QKQITKLLDQ EEEHRKIYEI QSEEIRQLKD VLKELHCCLE DEQKLLRDSE
     AQISSLKKQN TKLENAAQET ETLREAQVGE INSLLEQISF LQQELTVTQD AVKGLQLLND
     ELDMVNHSHA ELKKCMEDLG RSHSSTLEIK SNLENNLTEK NSLIITLKVE VQKLKEQMCQ
     DAESHTQQIN NCLNKQRWLQ EQLDEAKKIE TATKAESKSQ REEIKTMKTT LSAASQCLEE
     RDDLIESLKE KLCKAEEEQA KTSDLLREKV VSMNKVKVQM EMLQMDLEDN EMAMNTFNSQ
     VEELKATRDT LNSQLGQKQL QISDMEAKLE EYKAQVSVLE TRLEEVQSQN SLLEMQYITA
     KEELTERSCE VTCLEEGAVK ISQLNETVAA LQLKLGHITE ENNKLEKLRQ IMEGKDSDIN
     QLLQDKHILE TKVKQLIDEK ERVDANIIQV NAQKNHLEAS LNTLTEENQE LQSCMKWITE
     EKDKIDEVVL EKLEAKSSLR QVTEEKTQLA ATLSLLDQDK IQLETEVKEL AIEESNTVAK
     LNQVVDEKLQ LSCQCDQLTK ENIHLQSSLH KLAEDKLLMQ GSIQKFEKEM ISLEDKNKCI
     QSALLSSQQM VEILKEQLET QDKGAEERRE RSKQFEVQQV ALHQQLLVLQ MELAAMRQLY
     DSLLEQVSQQ NGFIQQLSDL QKTLKSEDNV SGRESKKTET VAGQMNADMT EDTSVESLPE
     MEQLSCEVAE LKEHSHQSEE DFCETQLVHK EHTGDKMMQE CLDVAKNVCV PDPLETVEEQ
     HLQQTEALNT SLSGLPSSSL PESSQSEISE KASPQVRDYL NNYKNIIISQ ENQLQQLYAE
     FDLLKSDLML RMELTSELQA EVQNWEKKFQ RAEEEKLVAL HKLNITLENH KVVTDQLTRL
     SEEKETLALQ LQTSKCQLTD VIEMLGGLQM TKGGWDDKFL QQESELKRVR SEKSNLEQHI
     LGMESDLENL QEERTKLKTE VETQRKVCSG MEQEIDTLRT ELTQLRAELV SCSEERDDLN
     QSLGQWRNKV DTLERTNCDT RNLISILEDD IRTGRREHKV LKTSIEELAS EKQQLLEQIK
     TLELAISEQN GERQELIGQL DKITEDHLSA HQNTETMVGK IQALEGEVYH LSQSLEASLV
     EKGEIASRLN STQDEVQQMR TDIEKLYIRI ESDERKKKKM RELLKAAQRK SDSLQDHIDA
     LVREHADIES SLEEAVLQAE TSKEELEEER RKVEEEKMVL SNKLSEFSIA LQHLRSEKKH
     VELELKNREI EDLKAAKEDM ERGLERAEAG KRQKEERQKH RVEQLEKEVK EDAERITRQL
     DDLRDQLQAC HQRELYLEGK SIETEADKER LKSLLADLEM DKNHLQTLLE ELQTGRDSLC
     SQTAERKREI HNLKTDINTL KEERNDLKIK IKAKEEEREN LQCSLVSLQG EKERIEQESQ
     VLVFDKEKLQ SYLCLIEKEK QEMQQILSSL KEEKDSIEEE RNDLAAEREE LLSLLFVVEK
     EKNDLSSITS SLEQENQNVE EKKEKLTGDQ GRLQSTVASV QEQLEMCKPS VSKRHEQVSD
     RTNVVTRLSK ERDSALSKMS RCMKTCKQLE QEKEVMLNSI DEVKNNAAQM EISQLQHAEK
     RNMDMEDLKM VLQQKKNEVE EQTKEVDELK AALIGREEEL MERNGELQEL KNELTKLKNI
     LEVKSMEADE SMDKYCNLMV QVHKLEETNA ALTTRLEQLS ASQNANNGKV VSDCVQHQRF
     TRKLAIKPRE ENLAVGNENT APSTPLRIPQ GSKRGHSDLS EKARHLPDLD LTKKIKTNLV
     NGAQEQTDQE DEDFRPEGLP ELVQKGFADI PVGEASPFII RRTTVKHYSS QLAGRHSVPT
     PVCKVLGPVS IHNPSKDSHM CLSPKQHPQS LGRTPEQKEK QTHQGDNCHV Q
//
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