ID H2TLD5_TAKRU Unreviewed; 543 AA.
AC H2TLD5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=CHST15 {ECO:0000313|Ensembl:ENSTRUP00000025490.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000025490.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000025490.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000025490.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|RuleBase:RU361155}.
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DR RefSeq; XP_011615651.1; XM_011617349.1.
DR AlphaFoldDB; H2TLD5; -.
DR STRING; 31033.ENSTRUP00000025490; -.
DR Ensembl; ENSTRUT00000025593.3; ENSTRUP00000025490.2; ENSTRUG00000010119.3.
DR GeneID; 101075284; -.
DR KEGG; tru:101075284; -.
DR CTD; 51363; -.
DR eggNOG; ENOG502QU6N; Eukaryota.
DR GeneTree; ENSGT00390000004719; -.
DR HOGENOM; CLU_017703_2_1_1; -.
DR InParanoid; H2TLD5; -.
DR OMA; HVDSKQM; -.
DR OrthoDB; 3939141at2759; -.
DR TreeFam; TF333516; -.
DR Proteomes; UP000005226; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR15723; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR PANTHER; PTHR15723:SF0; CARBOHYDRATE SULFOTRANSFERASE 15; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..483
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 543 AA; 63070 MW; 073C7AF163EB77CC CRC64;
MTQMDYKYSL LGSVADDYRK RPLLLQVDDT PMNLFAVLEV KREPPQRWGA LSGFRRIRIY
SFLFGLAVMF FITASYILTG DKKGLLLTPS PYHFSVLVSP GPLTFNLSVV KDDAHIREVV
RSIASKVELG SSRHLPDLKA LVNSEPHLFS VIPRKFLTGI KNPCWYEEYS GNVSSDPYRT
NLYAHYSKRF RTVFQHLRST FREHLIHRDG KAYRMRCLPY FYIIGQPKCG TTDLYDRLRL
HPDVKFTTFK EPHWWTRKRF GIIRLSEGFH DRYPVEDYLD LFDQAAYQIQ GNLSANVSAS
PSQPNVIIGE ASASTMWDNN AWVYFYDNTT EGEPPFLIQD FVHALQPHAR FIVMLRDPVE
RLYSDYLYFG ISNKSAEDFH EKVSESLQLF EGCLTEYTMR SCVYNTTVNN AMPVRLQVGL
YIVYLMDWLS VVSREQLLVL RLEDHATNRK YTMHRVFDFL DLEPPTKEIE AEITESPASN
TRRPADKNLG PMLPITKEIL GDFYRPFNIK LAKVLRNDSF IWDNNSKLQK PPPPPFLSST
ENH
//
