ID H2TLM9_TAKRU Unreviewed; 1500 AA.
AC H2TLM9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Nucleoporin 153 {ECO:0000313|Ensembl:ENSTRUP00000025584.3};
GN Name=nup153 {ECO:0000313|Ensembl:ENSTRUP00000025584.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000025584.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000025584.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000025584.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 31033.ENSTRUP00000025584; -.
DR Ensembl; ENSTRUT00000025688.3; ENSTRUP00000025584.3; ENSTRUG00000010163.3.
DR eggNOG; KOG4719; Eukaryota.
DR GeneTree; ENSGT00940000153253; -.
DR InParanoid; H2TLM9; -.
DR OMA; SASEWEC; -.
DR OrthoDB; 2920135at2759; -.
DR TreeFam; TF323517; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 4.
DR InterPro; IPR026054; Nucleoporin.
DR InterPro; IPR013913; Nup153_N.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR23193; NUCLEAR PORE COMPLEX PROTEIN NUP; 1.
DR PANTHER; PTHR23193:SF23; NUCLEAR PORE COMPLEX PROTEIN NUP153; 1.
DR Pfam; PF08604; Nup153; 1.
DR Pfam; PF00641; zf-RanBP; 4.
DR SMART; SM00547; ZnF_RBZ; 4.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 4.
DR PROSITE; PS01358; ZF_RANBP2_1; 4.
DR PROSITE; PS50199; ZF_RANBP2_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 655..685
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 723..752
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 792..821
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 849..878
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 613..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 683..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 878..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1013..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1144..1175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1358..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1276..1290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1372..1386
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1387..1402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1500 AA; 151427 MW; C537A2FD9E3A84D0 CRC64;
MAATGGGKIR SRRYHIATKP YAKNKQQQSG LISRVTDTVK SIVPSWLQKY FKNEDGPEGG
GTEEGRDQNC QLSPSPPQPP NGNEEAPPVD GRDSPEPSTS NTEPTTSRAS LNFHEFVLSR
PPLNRSHLHL TPLDAASPSL GPSNSLFSPP STSSAPGPFT TGFSLIKEIK DNLSQHEDDN
ISTTSGFSSR ASDKDVPTSK TASLPQLWSP EMDRSHTGPQ PSQSSLKRPS FNLSVFGTSS
NTSFNNTVLN SSQLGDSSFY PGKTTYGGAA AARSSRNRPG TPYQPPVRRQ IKAKPAGVQP
CGVTSATARR ILQSLERMSS PLADARRIPA SASSPLSTTL DSMIPDVPRS QAKKKRMDTN
LPPVQKLLVP SVAATARNRS MSFRPTLTPG GGGRPLDKAP AETPTRQSPQ LPEMSPRPSQ
STMGYSAPAY PLSSTPAANS VTFGGGKMKR ERSSARVSMK RHEEDGQPEL PDLPTISLPI
STSALPTFSF TSPLPASVIG NSSSITVTPG KDVLTAMETP AASSSPSVPF TFSSPIVKAA
PASTPISPSA GFTFSAPVAK GPSMSNGKLA NSKVAVKSAP CKSTEESDGL FKPAKTLKQG
SVLDLLKTPG FTSAVQTGPC PDDAPQQTTA SPPPTTAITT TSALSSSAGF GDLFKPPPGW
TCDACLVQNK PSDKKCVCCM TPQPNSSSTQ LDNKPSTATS VGLESSSTTS TTTAGFAAVF
AKPVGTWDCD TCLVRNKADA VKCVACETAK PGTGLKTSLT IPSAFSAIKA EAAPAPPVST
GFAGFGDKFK KAEGAWECDT CMVENKAEAT KCVACMNTKP GATTEAAAGA STPASSAPVL
GFGEAFKKPE GSWDCDVCLV QNKAADVECV ACQTPKPGAQ VDPKGKTGGA SSSSTFGSST
SNSGGFKFGT TEIITGSASE GFKFGGSFGD SSAAPTGFKF GVPFGSASSE TASQDSAASS
GFKFAGSSEG FKFGTASSDD KTSEPAAASG FKFGNSGGIM FGTGSSNAEI KSGFSFGATK
PDNKPPHATT SSTSAAPAAA APQEKSDGVT TNDVSDANAT AAATTTAATK ASVFARLGES
PAAPAPQASS VFGSLPTKEP AAPTFTFGKP EEKEAAQSPA PSGFVFGGAN KDVNAAPAPA
AKGGFTFGKP SAPAEQPPPV FSFGKAADTS ETTATEPPKA AFTFGQSAPD SSTAPKPAFS
FVFGNPTNSV AAAATTTAAA AAAAASSSSI TTPSLFGSST ASSQAPAPSA ASSTFMFGQT
ATSSGDGPPA KTAFVFGKSQ DSQPSAPSAA PPNSTASPAP AQPFMFGASA NAAAAPPAAA
PAFGFGAVAP SVTSSSAPSA ASSPFTFSSA PSGGFGASQA PSFGSFGSPF TAPPSQSPPT
FGANPNPNPT PVFGQQANST PAFGANANSS AGGGFQFGAS GFGATNNTSG VFTFGAGAAA
SPAPPANPAI PPQTGAAGPG FNFAQAPSFN IGSTKSFTAP PAGQQAIAGR KYKMAVRRRK
//
