ID H2U542_TAKRU Unreviewed; 698 AA.
AC H2U542;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Scm polycomb group protein like 2 {ECO:0000313|Ensembl:ENSTRUP00000032055.2};
GN Name=LOC101068319 {ECO:0000313|Ensembl:ENSTRUP00000032055.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000032055.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000032055.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000032055.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2U542; -.
DR STRING; 31033.ENSTRUP00000032055; -.
DR Ensembl; ENSTRUT00000032178.3; ENSTRUP00000032055.2; ENSTRUG00000012660.3.
DR GeneTree; ENSGT00940000159407; -.
DR HOGENOM; CLU_015000_1_0_1; -.
DR InParanoid; H2U542; -.
DR OMA; TEEPICC; -.
DR Proteomes; UP000005226; Chromosome 20.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20092; MBT_dScm-like_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF84; SEX COMB ON MIDLEG-LIKE PROTEIN 2; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 27..125
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 133..234
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 272..333
FT /note="Polycomb group protein RNA binding region"
FT /evidence="ECO:0000259|Pfam:PF17208"
FT DOMAIN 356..465
FT /note="SLED"
FT /evidence="ECO:0000259|Pfam:PF12140"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 77145 MW; 32CC9E77765B05F2 CRC64;
MGKTPVKDQK DGKKDKPGRT IPATDAFSWE DYLKETSSIP APPSCFRQAR IPPSNDFKVG
MKLEAHDPRN STSVCIATVM GLTGVRLRLR LDGSDNSNDF WRLVDSSDIQ PIGTCEKNGD
MLQPPLGFRM NASSWPMFLL RTLNGAEMAP ATAFKKEPIR PSQNNFKPGM KLEAVDKKNP
YLICPATIGE VKGDEVFIMF DGWRGAFDYW CKYDSRDIFP VGWCSLTKHS LQPPGNSVTL
PKHLQILPVS PSKPNRRSMQ PPYRLPNPLP PLPVRKGVRG RRPKSETIAL LKAVAEAAAV
HGAIPDNHQL VPRPHKKRGP KPGSKRKPKI LQSPAQVPSI QVPREGPLGH NSVVSTVCVY
VNKHGNCGPH LDRKQMQHLP DHFGPGPVNK VLQQVVQSCI DSAYQPKILL SALQTHSGGG
EAVRVRTDGG VRVVKLPAAS SASFVLRFLE MMCRHLQCDN LFSSQPFSHY AAYDRTKSVK
EEALDTPSLI RGSKRSLSGV SPPYAAPLSP KHLRAEAHPS EAETLPHEEN VLMKEQRYMD
SASNSMTPRP QTLRSSSEYH SKVNSLYHST GSSAPIRRLA SNPTELSATP PHRRVEAASS
TTGPESLVSE RDGAQLPGKN PSSWSIDEVM QFVRDADPTA LAPHAELFRK HVSPLKSRDR
LFVLAPAPLS PFFLLRSSQQ FDTTRLVLCL CRRSMEKL
//
